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ADAM33

From SNPedia

is agene
is mentioned by
EntrezGene80332
PheGenI80332
VariationViewer80332
ClinVarADAM33
dbSNP80332
SADR80332
HugeNav80332
wikipediaADAM33
googleADAM33
gopubmedADAM33
EVSADAM33
HEFalMpADAM33
MyGene2ADAM33
23andMeADAM33
# SNPs22
 Max MagnitudeChromosome positionSummary
rs22800893,669,480
rs228009003,669,558
rs22800913,669,587
rs27870933,667,815
rs27870943,668,514
rs28532093,670,825
rs39183913,675,071
rs39183923,674,572
rs39183963,671,118
rs415348473,673,835
rs447073,670,579
rs5118983,674,438
rs5126253,667,731
rs5285573,671,095
rs5437492.13,669,032
rs57417403,670,047
rs5979803,670,518
rs61270903,671,560
rs6154363,672,188
rs6289773,669,074
rs6770443,668,784
rs6788813,669,156


SNPs in the ADAM33 gene have been linked to a predisposition to asthma and bronchial hyperresponsiveness. [PMID 12110844, PMID 14564349]

These SNPs include:

At an individual level, another study [PMID 16773130] has found no association between any individual ADAM33 SNP and asthma predisposition, but they did find an association with ADAM33 haplotypes, leading to the conclusion that either some ADAM33 SNPs or SNPs in another gene located nearby are associated with asthma.

SNPs in the ADAM33 gene have also been linked to increased risk for chronic obstructive pulmonary disease among those who choose to smoke. The most significant of these ADAM33 SNPs are: