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ANG

From SNPedia

is agene
is mentioned by
Full nameangiogenin, ribonuclease, RNase A family, 5
EntrezGene283
PheGenI283
VariationViewer283
ClinVarANG
dbSNP283
SADR283
HugeNav283
wikipediaANG
googleANG
gopubmedANG
EVSANG
HEFalMpANG
MyGene2ANG
23andMeANG
UniProtP03950
EnsemblENSG00000214274
OMIM105850
# SNPs12
 Max MagnitudeChromosome positionSummary
rs1170120,693,894
rs121909535020,693,671
rs121909536020,693,686
rs121909537020,693,685
rs121909538020,693,728
rs121909539020,693,753
rs121909540020,693,755
rs121909541020,693,772
rs121909542020,693,719
rs121909543020,693,971
rs121909544020,693,973
rs1711469920,690,751

A variation in the ANG (angiogenin) gene, rs11701, appears to be associated with ALS in Scottish and Irish populations, although not in several other populations tested, including the U.S.(Boston), England, and Sweden [PMID 16501576].


[PMID 15557516] In Irish ALS patients, there was a significant allelic association with the rs11701 SNP & a new mutation (K40I) that potentially inhibits angiogenin function.