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Acetylcholine/all

From SNPedia

Acetylcholine synthesis[edit]

 On chromosomeChromosome positionIn geneSummary
rs8858341049,607,466CHAT
rs733722(C;C)1049,608,897CHAT
SLC18A3
no positive effect of AChE inhibitors for Alzheimer's patients
rs733722(C;T)1049,608,897CHAT
SLC18A3
some positive effect of AChE inhibitors for Alzheimer's patients
rs7337221049,608,897CHAT
SLC18A3
rs733722(T;T)1049,608,897CHAT
SLC18A3
largest positive effect of AChE inhibitors for Alzheimer's patients
rs18806761049,616,071CHAT
rs38109501049,616,573CHAT
rs3810950(G;G)1049,616,573CHATcommon in clinvar
rs794727516(C;C)1049,619,755CHATcommon in clinvar
rs7947275161049,619,755CHAT
rs1219128201049,620,544CHAT
rs121912820(T;T)1049,620,544CHATcommon in clinvar
rs28930071(T;T)1049,620,544CHAT
rs289300711049,620,544CHAT
rs1219128151049,620,546CHAT
rs121912815(C;C)1049,620,546CHATcommon in clinvar
rs81789901049,622,125CHAT
rs8178990(C;C)1049,622,125CHATcommon in complete genomics
rs754660541049,625,634CHAT
rs28929482(T;T)1049,625,634CHAT
rs75466054(T;T)1049,625,634CHATcommon in clinvar
rs289294821049,625,634CHAT
rs121912823(T;T)1049,627,681CHATcommon in clinvar
rs1219128231049,627,681CHAT
rs2177369(C;T)1049,635,683CHATnormal
rs2177369(T;T)1049,635,683CHATnormal
rs21773691049,635,683CHAT
rs2177369(C;C)1049,635,683CHAT1.5x increased risk for Alzheimer's disease
rs1219128221049,646,651CHAT
rs121912822(C;C)1049,646,651CHATcommon in clinvar
rs121912816(G;G)1049,648,546CHATcommon in clinvar
rs289300701049,648,546CHAT
rs1219128161049,648,546CHAT
rs28930070(G;G)1049,648,546CHAT
rs4838544(G;G)1049,648,606CHATcommon in clinvar
rs48385441049,648,606CHAT
rs4838544(A;A)1049,648,606CHATcommon in complete genomics
rs121912818(A;A)1049,649,569CHATcommon in clinvar
rs289294811049,649,569CHAT
rs1219128181049,649,569CHAT
rs28929481(A;A)1049,649,569CHAT
rs1219128211049,649,618CHAT
rs121912821(C;C)1049,649,618CHATcommon in clinvar
rs1219128171049,651,888CHAT
rs121912817(G;G)1049,651,888CHATcommon in clinvar
rs1219128191049,655,139CHAT
rs121912819(G;G)1049,655,139CHATcommon in clinvar
rs122515141050,500,034SGMS1

Acetylcholine degradation[edit]

Acetylcholine transporter[edit]

 On chromosomeChromosome positionIn geneSummary
rs7337221049,608,897CHAT
SLC18A3
rs733722(C;C)1049,608,897CHAT
SLC18A3
no positive effect of AChE inhibitors for Alzheimer's patients
rs733722(C;T)1049,608,897CHAT
SLC18A3
some positive effect of AChE inhibitors for Alzheimer's patients
rs733722(T;T)1049,608,897CHAT
SLC18A3
largest positive effect of AChE inhibitors for Alzheimer's patients

Acetylcholine receptors[edit]

Nicotinic acetylcholine receptors[edit]

alpha[edit]

 On chromosomeChromosome positionIn geneSummary
rs37432001578,981,704CHRNA1
RASGRF1
rs193922162794,417,733CHRNA1
COL1A2
rs193922162(G;G)794,417,733CHRNA1
COL1A2
common in clinvar
rs3736638794,417,954CHRNA1
COL1A2
rs72658152794,418,508CHRNA1
COL1A2
rs72658152(G;G)794,418,508CHRNA1
COL1A2
common in clinvar
rs72658154(G;G)794,418,518CHRNA1
COL1A2
common in clinvar
rs72658154794,418,518CHRNA1
COL1A2
rs72658163794,420,276CHRNA1
COL1A2
rs72658163(G;G)794,420,276CHRNA1
COL1A2
common in complete genomics
rs72658176(G;G)794,420,604CHRNA1
COL1A2
common in clinvar
rs72658176794,420,604CHRNA1
COL1A2
rs72658200(G;G)794,424,345CHRNA1
COL1A2
common in clinvar
rs72658200794,424,345CHRNA1
COL1A2
rs441051794,424,688CHRNA1
COL1A2
rs193922165794,425,655CHRNA1
COL1A2
rs193922165(G;G)794,425,655CHRNA1
COL1A2
common in clinvar
rs72659319(G;G)794,426,459CHRNA1
COL1A2
common in clinvar
rs72659319794,426,459CHRNA1
COL1A2
rs2621215794,426,732CHRNA1
COL1A2
rs193922166794,427,006CHRNA1
COL1A2
rs193922166(A;A)794,427,006CHRNA1
COL1A2
common in clinvar
rs193922167794,427,643CHRNA1
COL1A2
rs193922167(C;C)794,427,643CHRNA1
COL1A2
common in clinvar
rs72659338794,427,654CHRNA1
COL1A2
rs72659338(G;G)794,427,654CHRNA1
COL1A2
common in complete genomics
rs193922168794,427,714CHRNA1
COL1A2
rs193922168(G;G)794,427,714CHRNA1
COL1A2
common in clinvar
rs72659343794,428,367CHRNA1
COL1A2
rs72659343(G;G)794,428,367CHRNA1
COL1A2
common in clinvar
rs1378528082174,748,184CHRNA1
rs137852808(C;C)2174,748,184CHRNA1common in clinvar
rs137852804(G;G)2174,750,035CHRNA1common in clinvar
rs1378528042174,750,035CHRNA1
rs1378528022174,750,082CHRNA1
rs137852802(G;G)2174,750,082CHRNA1common in clinvar
rs137852806(T;T)2174,750,122CHRNA1common in clinvar
rs1378528062174,750,122CHRNA1
rs1378528002174,750,127CHRNA1
rs137852800(C;C)2174,750,127CHRNA1common in clinvar
rs1378528032174,750,143CHRNA1
rs137852803(G;G)2174,750,143CHRNA1common in clinvar
rs137852805(T;T)2174,753,524CHRNA1common in clinvar
rs1378528052174,753,524CHRNA1
rs4833530462174,753,544CHRNA1
rs483353046(C;C)2174,753,544CHRNA1common in clinvar
rs1378527982174,753,570CHRNA1
rs137852798(C;C)2174,753,570CHRNA1common in clinvar
rs5455208062174,753,594CHRNA1
rs545520806(G;G)2174,753,594CHRNA1common in clinvar
... further results
 On chromosomeChromosome positionIn geneSummary
rs104894063827,463,607CHRNA2
rs104894063(T;T)827,463,607CHRNA2common in clinvar
rs3735757827,464,080CHRNA2
rs2472553827,470,994CHRNA2
 On chromosomeChromosome positionIn geneSummary
rs81924821578,593,856CHRNA3
CHRNA5
rs48870671578,594,605CHRNA3
CHRNA5
rs6606521578,595,490CHRNA3
CHRNA5
rs5787761578,596,058CHRNA3
rs129109841578,599,285CHRNA3
rs10517301578,601,997CHRNA3smoking and drinking
rs1051730(C;C)1578,601,997CHRNA3Smokes normal (lower) number of cigarettes if a smoker.
rs1051730(T;T)1578,601,997CHRNA31.8x increased risk of lung cancer; reduced response to alcohol, therefore possibly increased risk of alcohol abuse
rs1051730(C;T)1578,601,997CHRNA31.3x increased risk of lung cancer
rs37430781578,602,417CHRNA3
rs37430771578,602,554CHRNA3
rs13172861578,603,787CHRNA3
rs9386821578,604,205CHRNA3
rs129143851578,606,381CHRNA3
rs64953081578,615,314CHRNA3
rs80423741578,615,690CHRNA3May affect lung cancer risk
rs3743076(A;A)1578,616,885CHRNA3common in complete genomics
rs37430761578,616,885CHRNA3
rs37430731578,617,197CHRNA3
rs80408681578,618,839CHRNA3
rs80234621578,622,392CHRNA3
rs64953091578,622,903CHRNA3
 On chromosomeChromosome positionIn geneSummary
rs45226662063,343,128CHRNA4
rs22361962063,346,204CHRNA4
rs2236196(A;A)2063,346,204CHRNA4common in complete genomics
rs37871372063,347,748CHRNA4
rs10443972063,349,752CHRNA4
rs1044396(C;C)2063,349,782CHRNA4Increased risk of Nicotine dependence among males
rs10443962063,349,782CHRNA4
rs281865068(G;G)2063,350,404CHRNA4common in clinvar
rs2818650682063,350,404CHRNA4
rs281865066(C;C)2063,350,533CHRNA4common in clinvar
rs2818650662063,350,533CHRNA4
rs2818650672063,350,538CHRNA4
rs281865067(;)2063,350,538CHRNA4common in clinvar
rs289315912063,350,560CHRNA4
rs28931591(C;C)2063,350,560CHRNA4common in clinvar
rs28931591(G;G)2063,350,560CHRNA4
rs1219095802063,350,572CHRNA4
rs121909580(C;C)2063,350,572CHRNA4common in clinvar
rs1044394(C;C)2063,350,733CHRNA4common in complete genomics
rs1044394(T;T)2063,350,733CHRNA4common in clinvar
rs10443942063,350,733CHRNA4
rs7960523172063,350,867CHRNA4
rs796052317(T;T)2063,350,867CHRNA4common in clinvar
rs1219122432063,350,969CHRNA4
rs121912243(C;C)2063,350,969CHRNA4common in clinvar
rs22735022063,356,470CHRNA4
rs22735042063,356,709CHRNA4
rs2273505(C;C)2063,359,526CHRNA4
RP11-261N11.8
common in complete genomics
rs22735052063,359,526CHRNA4
RP11-261N11.8
rs7552042063,362,813CHRNA4
RP11-261N11.8
 On chromosomeChromosome positionIn geneSummary
rs38297871578,563,924CHRNA5
rs5034641578,565,554CHRNA5
rs558536981578,565,597CHRNA5
rs557815671578,565,644CHRNA5
rs6845131578,566,058CHRNA5
rs6672821578,571,130CHRNA5
rs5887651578,573,083CHRNA5
rs64953061578,573,551CHRNA5
rs6495306(G;G)1578,573,551CHRNA5
rs174862781578,575,140CHRNA5
rs6010791578,577,237CHRNA5
rs4959561578,577,588CHRNA5
rs6802441578,578,946CHRNA5
rs5692071578,580,777CHRNA5
rs116376351578,584,808CHRNA5
rs9512661578,586,199CHRNA5
rs5550181578,586,900CHRNA5
rs128989191578,588,235CHRNA5
rs174082761578,589,276CHRNA5
rs16969968(A;A)1578,590,583CHRNA5higher risk for nicotine dependence, lower risk for cocaine dependence
rs16969968(A;G)1578,590,583CHRNA5slightly higher risk for nicotine dependence, lower risk for cocaine dependence
rs169699681578,590,583CHRNA5
rs16969968(G;G)1578,590,583CHRNA5normal
rs81924821578,593,856CHRNA3
CHRNA5
rs48870671578,594,605CHRNA3
CHRNA5
rs6606521578,595,490CHRNA3
CHRNA5
rs38413241578,857,813CHRNA5
 On chromosomeChromosome positionIn geneSummary
rs4952842,731,922CHRNB3
rs4953842,732,516CHRNB3
rs4953(G;G)842,732,516CHRNB3common in complete genomics
rs4954842,732,653CHRNB3
rs2304297842,753,056CHRNA6
rs7812298842,753,436CHRNA6
rs16891604842,763,570CHRNA6
 On chromosomeChromosome positionIn geneSummary
rs30874541532,028,764CHRNA7
rs8834731532,033,473CHRNA7
rs23375061532,053,864CHRNA7
rs47799691532,056,728CHRNA7
rs13559201532,065,525CHRNA7
rs21339651532,092,351CHRNA7
rs6494223(T;T)1532,104,256CHRNA7in ALZ patients, increased risk of delusions
rs64942231532,104,256CHRNA7
rs6494223(C;C)1532,104,256CHRNA7normal
rs6494223(C;T)1532,104,256CHRNA7in ALZ patients, increased risk of delusions
rs9049521532,126,544CHRNA7
rs19098841532,147,097CHRNA7
rs71781761532,151,612CHRNA7
rs23379801532,151,995CHRNA7
 On chromosomeChromosome positionIn geneSummary
rs17585937440,044,067TRRAP
rs17585937(C;C)440,044,067TRRAP
rs73229797440,334,646CHRNA9
rs56159866440,335,927CHRNA9
rs55998310440,337,233CHRNA9
rs55998310(T;T)440,337,233CHRNA9common in complete genomics
rs6819385440,337,557CHRNA9
rs55633891440,354,024CHRNA9
rs10009228440,354,405CHRNA9
rs56291234440,354,882CHRNA9

beta[edit]

 On chromosomeChromosome positionIn geneSummary
rs17856697177,445,306CHRNB1
FGF11
rs17856697(A;A)177,445,306CHRNB1
FGF11
common in clinvar
rs2302765(A;A)177,447,656CHRNB1common in clinvar
rs2302765177,447,656CHRNB1
rs137852811177,454,329CHRNB1
rs137852811(C;C)177,454,329CHRNB1common in clinvar
rs137852810177,454,341CHRNB1
rs137852810(G;G)177,454,341CHRNB1common in clinvar
rs2302762177,455,542CHRNB1
rs2302762(T;C)177,455,542CHRNB1
rs2302762(C;C)177,455,542CHRNB1
rs2302763177,455,958CHRNB1
 On chromosomeChromosome positionIn geneSummary
rs67012161152,806,050LCE1C
rs74315291(G;G)1154,571,682CHRNB2common in clinvar
rs743152911154,571,682CHRNB2
rs2818650691154,571,724CHRNB2
rs281865069(C;C)1154,571,724CHRNB2common in clinvar
rs2818650701154,571,746CHRNB2
rs281865070(T;T)1154,571,746CHRNB2common in clinvar
rs281865071(C;C)1154,571,759CHRNB2common in clinvar
rs2818650711154,571,759CHRNB2
rs281865072(T;T)1154,571,833CHRNB2common in clinvar
rs2818650721154,571,833CHRNB2
rs4845378(G;G)1154,572,175CHRNB2common in clinvar
rs48453781154,572,175CHRNB2
rs20726601154,576,245CHRNB2
rs20726611154,576,404CHRNB2
 On chromosomeChromosome positionIn geneSummary
rs7842601842,681,912
rs13273442842,688,874
rs1451240842,691,568
rs13277254842,694,839
rs6474412842,695,355
rs6474413842,695,921CHRNB3
rs4950842,697,490CHRNB3
rs13261190842,723,166CHRNB3
rs4952842,731,922CHRNB3
rs4953(G;G)842,732,516CHRNB3common in complete genomics
rs4953842,732,516CHRNB3
rs4954842,732,653CHRNB3
 On chromosomeChromosome positionIn geneSummary
rs19481578,625,057CHRNB4
rs71782701578,628,735CHRNB4
rs562188661578,629,887CHRNB4
rs129140081578,631,163CHRNB4
rs17487223(T;T)1578,631,645CHRNB41.28x lung cancer risk
rs174872231578,631,645CHRNB4
rs17487223(C;T)1578,631,645CHRNB4Higher lung cancer risk?
rs17487223(C;C)1578,631,645CHRNB4normal
rs9507761578,633,676CHRNB4
rs116367531578,636,604CHRNB4

delta/epsilon/gamma[edit]

 On chromosomeChromosome positionIn geneSummary
rs5548266462232,524,355CHRND
PRSS56
rs554826646(G;G)2232,524,355CHRND
PRSS56
common in clinvar
rs7308821622232,525,249CHRND
PRSS56
rs730882162(G;G)2232,525,249CHRND
PRSS56
common in clinvar
rs617444042232,525,489CHRND
PRSS56
rs61744404(C;C)2232,525,489CHRND
PRSS56
common in clinvar
rs7970444802232,526,549CHRND
rs797044480(G;G)2232,526,549CHRNDcommon in clinvar
rs1219095082232,526,664CHRND
rs121909508(T;T)2232,526,664CHRNDcommon in clinvar
rs121909505(G;G)2232,527,436CHRNDcommon in clinvar
rs1219095052232,527,436CHRND
rs121909509(T;T)2232,527,438CHRNDcommon in clinvar
rs1219095092232,527,438CHRND
rs121909504(G;G)2232,527,440CHRNDcommon in clinvar
rs1219095042232,527,440CHRND
rs1219095062232,528,301CHRND
rs121909506(T;T)2232,528,301CHRNDcommon in clinvar
rs121909503(C;C)2232,530,131CHRNDcommon in clinvar
rs1219095032232,530,131CHRND
rs1219095022232,531,397CHRND
rs121909502(C;C)2232,531,397CHRNDcommon in clinvar
rs124663582232,532,815CHRND
rs145955590(G;G)2232,534,087CHRNDcommon in clinvar
rs1459555902232,534,087CHRND
rs3737470902232,534,290CHRND
rs373747090(A;A)2232,534,290CHRNDcommon in clinvar
rs1219095072232,535,148CHRND
rs121909507(C;C)2232,535,148CHRNDcommon in clinvar
 On chromosomeChromosome positionIn geneSummary
rs1045280174,719,343ARRB2
rs2036657174,721,864ARRB2
rs1051009174,734,591CXCL16
rs3744700174,734,715CXCL16
rs2277680174,735,268CXCL16
rs2250333174,738,774CXCL16
ZMYND15
rs2304973174,738,927CXCL16
ZMYND15
rs2304973(C;C)174,738,927CXCL16
ZMYND15
common in complete genomics
rs587777432174,744,214ZMYND15
rs587777432(AAAC;AAAC)174,744,214ZMYND15common in clinvar
rs773526895174,898,864C17orf107
CHRNE
rs773526895(;)174,898,864C17orf107
CHRNE
common in clinvar
rs763258280174,898,891C17orf107
CHRNE
rs763258280(C;C)174,898,891C17orf107
CHRNE
common in clinvar
rs121909517(G;G)174,899,036CHRNE
C17orf107
common in clinvar
rs121909517174,899,036CHRNE
C17orf107
rs786204773174,899,386C17orf107
CHRNE
rs786204773(A;A)174,899,386C17orf107
CHRNE
common in clinvar
rs879253723174,899,470C17orf107
CHRNE
rs879253723(C;C)174,899,470C17orf107
CHRNE
common in clinvar
rs121909515174,899,509CHRNE
C17orf107
rs121909515(C;C)174,899,509CHRNE
C17orf107
common in clinvar
rs398122830174,900,816C17orf107
CHRNE
rs398122830(TCT;TCT)174,900,816C17orf107
CHRNE
common in clinvar
rs121909511174,900,845CHRNE
C17orf107
rs121909511(C;C)174,900,845CHRNE
C17orf107
common in clinvar
rs121909510174,900,860CHRNE
C17orf107
rs121909510(A;A)174,900,860CHRNE
C17orf107
common in clinvar
rs28999110(C;C)174,901,071CHRNE
C17orf107
common in clinvar
rs28999110174,901,071CHRNE
C17orf107
rs28999110(G;G)174,901,071CHRNE
C17orf107
rs201434993174,901,082C17orf107
CHRNE
rs201434993(C;C)174,901,082C17orf107
CHRNE
common in clinvar
rs753828284(ATGGCCC;ATGGCCC)174,901,172C17orf107
CHRNE
common in clinvar
rs753828284174,901,172C17orf107
CHRNE
rs121909514(G;G)174,901,932CHRNE
C17orf107
common in clinvar
rs121909514174,901,932CHRNE
C17orf107
rs121909516(C;C)174,901,944CHRNE
C17orf107
common in clinvar
rs121909516174,901,944CHRNE
C17orf107
rs121909512(C;C)174,902,010CHRNE
C17orf107
common in clinvar
rs121909512174,902,010CHRNE
C17orf107
rs483353045174,902,011C17orf107
CHRNE
rs483353045(C;C)174,902,011C17orf107
CHRNE
common in clinvar
rs879253722174,902,216C17orf107
CHRNE
rs879253722(G;G)174,902,216C17orf107
CHRNE
common in clinvar
rs28929768(T;T)174,902,268CHRNE
C17orf107
common in clinvar
rs28929768174,902,268CHRNE
C17orf107
rs28929768(A;A)174,902,268CHRNE
C17orf107
rs121909513(C;C)174,902,311CHRNE
C17orf107
common in clinvar
rs121909513174,902,311CHRNE
C17orf107
... further results
 On chromosomeChromosome positionIn geneSummary
rs2676067252232,539,760CHRNG
rs267606725(C;C)2232,539,760CHRNGcommon in clinvar
rs7862055492232,539,803CHRNG
rs786205549(G;G)2232,539,803CHRNGcommon in clinvar
rs7970446772232,540,053CHRNG
rs1219126722232,540,072CHRNG
rs121912672(C;C)2232,540,072CHRNGcommon in clinvar
rs8632233132232,540,670CHRNG
rs267606726(T;T)2232,540,681CHRNGcommon in clinvar
rs2676067262232,540,681CHRNG
rs7657467952232,541,451CHRNG
rs765746795(C;C)2232,541,451CHRNGcommon in clinvar
rs18814922232,542,288CHRNG
rs1219126702232,542,992CHRNG
rs121912670(C;C)2232,542,992CHRNGcommon in clinvar
rs7675030382232,543,030CHRNG
rs121912671(C;C)2232,545,570CHRNGcommon in clinvar
rs1219126712232,545,570CHRNG

Muscarinic acetylcholine receptors[edit]

 On chromosomeChromosome positionIn geneSummary
rs20772241162,429,955
rs171572661162,432,345AHNAK
rs118237281162,909,330CHRM1
rs5449781162,917,758CHRM1
rs2186410(G;G)1162,917,945CHRM1
rs21864101162,917,945CHRM1
rs5422691162,918,065CHRM1
 On chromosomeChromosome positionIn geneSummary
rs13644027136,899,616CHRM2
LOC349160
rs78104737136,911,710CHRM2
LOC349160
rs14558587136,946,956CHRM2
LOC349160
rs23507827136,957,887CHRM2
LOC349160
rs18240247136,958,947CHRM2
LOC349160
rs20611747136,976,653CHRM2
LOC349160
rs324640(G;G)7137,004,249CHRM2
LOC349160
rs3246407137,004,249CHRM2
LOC349160
rs324640(A;A)7137,004,249CHRM2
LOC349160
rs324640(A;G)7137,004,249CHRM2
LOC349160
rs3246507137,008,914CHRM2
LOC349160
rs324650(T;T)7137,008,914CHRM2
LOC349160
rs324650(A;T)7137,008,914CHRM2
LOC349160
rs324650(A;A)7137,008,914CHRM2
LOC349160
rs81919927137,016,561CHRM2
LOC349160
 On chromosomeChromosome positionIn geneSummary
rs6934211237,935,790
rs24996041237,940,201
rs133739411239,480,871CHRM3
rs23552301239,621,865CHRM3
rs2355230(A;A)1239,621,865CHRM3
rs2165870(A;G)1239,622,120CHRM32x higher risk for post-operative nausea
rs2165870(A;A)1239,622,120CHRM32x higher risk for post-operative nausea
rs2165870(G;G)1239,622,120CHRM3
rs21658701239,622,120CHRM3
rs108027891239,669,380CHRM3
rs6855501239,761,108CHRM3
rs120595461239,806,797CHRM3
rs75485221239,835,325CHRM3
rs7548522(C;C)1239,835,325CHRM3common in complete genomics
rs5364771239,882,608CHRM3
rs75209741239,903,960CHRM3
rs5877768621239,908,624CHRM3
rs587776862(GCCTGAGGAGGA;GCCTGAGGAGGA)1239,908,624CHRM3common in clinvar
 On chromosomeChromosome positionIn geneSummary
rs729100921146,384,943CHRM4
rs20674821146,385,217CHRM4
 On chromosomeChromosome positionIn geneSummary
rs64942231532,104,256CHRNA7
rs6494223(C;C)1532,104,256CHRNA7normal
rs6494223(C;T)1532,104,256CHRNA7in ALZ patients, increased risk of delusions
rs6494223(T;T)1532,104,256CHRNA7in ALZ patients, increased risk of delusions
rs9049521532,126,544CHRNA7
rs19098841532,147,097CHRNA7