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Anorexia nervosa

From SNPedia

Anorexia nervosa is an eating disorder characterized by refusal to maintain a healthy body weight, and an obsessive fear of gaining weight due to a distorted self image. It is a serious mental illness with a high incidence of comorbidity and one of the highest mortality rates of any psychiatric disorder.Wikipedia Anorexia is known to be heritable. This 2009 review discusses the genetics of anorexia nervosa [1]. A 2013 paper investigates possible association of anorexia nervosa with obsessive compulsive disorder OCD [PMID 23337130]. A 2014 GWAS study is currently in press [PMID 24514567]. DNA variations in these genes may be associated with anorexia nervosa:

  • DRD4, dopamine D4 receptor
    • [rs1800955]]


GWAS studies on anorexia nervosɑ[edit]

[PMID 24514567OA-icon.png] A genome-wide association study of anorexia nervosa.

[PMID 23568457OA-icon.png] Genetic variants associated with disordered eating. A genome-wide association study on common SNPs and rare CNVs in anorexia nervosa.

[PMID 23568457OA-icon.png] Genetic variants associated with disordered eating.

SNPs associated with anorexia nervosa based on GWAS studiesː