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CCR2

From SNPedia

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# SNPs2
 Max MagnitudeChromosome positionSummary
rs103438246,361,910
rs1799864046,357,717


CCR2 is a chemokine receptor gene; some of these receptors, most notably CCR5, are targets for HIV infection and thus the potential of the development of AIDS.

Compared with individuals without CCR5-Delta32 (a variation in another gene) or the CCR2 rs1799864(A) allele, individuals with one or two copies of rs1799864(A) had a 58% lower risk of developing AIDS during the first 4 years after testing positive for HIV, a 19% lower risk during the subsequent 4 years, and no significant protection thereafter. [PMID 12556692] No protective effect (ie no benefit) was seen for this SNP once AIDS had developed. [PMID 11694103]