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CDH1

From SNPedia

is agene
is mentioned by
Full namecadherin 1, type 1, E-cadherin (epithelial)
EntrezGene999
PheGenI999
VariationViewer999
ClinVarCDH1
dbSNP999
SADR999
HugeNav999
wikipediaCDH1_(gene)
googleCDH1
gopubmedCDH1
EVSCDH1
HEFalMpCDH1
MyGene2CDH1
23andMeCDH1
UniProtP12830
EnsemblENSG00000039068
OMIM192090
# SNPs81
 Max MagnitudeChromosome positionSummary
I5004969
I5004970
I5004971
I5004972
I5004974
I5004975
I5994973
rs1043192368,805,360
rs116093741068,812,144
rs1164241368,756,491
rs121964871068,823,593
rs121964872068,833,362
rs121964873068,810,290
rs121964874068,823,557
rs121964875068,738,307
rs121964876068,738,318
rs121964877068,822,081
rs121964878068,822,190
rs1259718868,780,923
rs1368968,834,619
rs16260068,737,131
rs1695838368,823,097
rs1769055468,835,607
rs180102668,833,553
rs1801552068,823,538
rs186274868,799,040
rs20211558968,819,424
rs267606712568,811,859
rs2837278368,737,219
rs33935154068,822,138
rs35572355568,833,344
rs37034599668,829,757
rs37615250668,801,888
rs478357368,806,685
rs478367368,758,190
rs572272864068,737,353
rs587776398568,812,149
rs587780113568,815,760
rs58778011968,829,701
rs587780537568,810,224
rs587780784568,811,854
rs587780787568,828,296
rs587781276568,823,526
rs587781290068,808,557
rs58778133568,829,754
rs587781919068,801,894
rs587782359568,812,244
rs58778267768,801,859
rs587782750568,822,210
rs587782798568,813,322
... further results


The CDH1 gene encodes the cadherin-1 protein, also known as CAM 120/80 or epithelial cadherin (E-cadherin). It is a tumor suppressor gene, and mutations in this gene have been associated with various cancers including breast cancer and hereditary diffuse gastric cancer.

Mutations considered pathogenic and acting in a dominant manner for gastric cancer, hereditary cancer-predisposing syndrome and related cancers include:

rsid 23andMe term synonyms (c. or p.) OMIM On chip?
rs572272864 c.-63C>A
rs749591910 c.48+5G>C
rs121964875 i5004971 c.59G>A 192090.0009 Ancestry v2
rs786203576 i5004970 c.60G>A
rs121964876 i5004972 c.70G>T 192090.0011 Ancestry v2
rs786201058 c.76G>T
rs876658865 c.124_126delCCCinsT
rs786203727 c.185G>T
rs587783047 c.187C>T Ancestry v2
rs786202151 c.202delT
rs781409616 c.283C>T
rs587782677 c.353C>G
rs746703615 c.377delC
rs376152506 c.382delC
rs864622655 c.504delA
rs587780537 c.715G>A Ancestry v2
rs587780784 c.1003C>T
rs267606712 c.1008G>T 192090.0005 Ancestry v2
rs786201045 c.1009_1010delAG
rs116093741 i5004975 c.1018A>G 192090.0016 Ancestry v2
rs587776398 c.1023T>G
rs863224505 c.1063delT
rs869312764 c.1064delT
rs587782359 c.1118C>T Ancestry v2
rs587783050 c.1137G>A Ancestry v2
rs876660771 c.1137+1G>A
rs587782798 c.1147C>T Ancestry v2
rs876659208 c.1476_1477delAG
rs876658261 c.1488_1494delCGAGGAC
rs869312765 c.1505delG
rs587780113 c.1565+1G>T
rs587780113 c.1565+1G>A
rs730881667 c.1610delC
rs202115589 c.1710delT
rs786202290 c.1711+5G>A
rs121964877 i5994973 c.1792C>T 192090.0012 Ancestry v2
rs121964878 i5004974 c.1901C>T 192090.0015 Ancestry v2
rs587782750 c.1921C>T Ancestry v2
rs730881653 c.1979dupT Ancestry v2
rs786202033 c.1999delC
rs587781276 c.2064_2065delTG
rs121964874 i5004969 c.2095C>T 192090.0007 Ancestry v2
rs776975632 c.2245C>T
rs587780787 c.2287G>T Ancestry v2
rs754162869 c.2310delC
rs587780119 c.2343A>T
rs587781335 c.2396C>G
rs587783048 c.2398delC Ancestry v2
rs370345996 c.2399delG
rs786203752 c.2430delT
rs35572355 rs35572355 c.2494G>A 192090.0017 23andMe v1, 23andMe v3, 23andMe v4, Ancestry v2