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CNTNAP2

From SNPedia

is agene
is mentioned by
EntrezGene26047
PheGenI26047
VariationViewer26047
ClinVarCNTNAP2
dbSNP26047
SADR26047
HugeNav26047
wikipediaCNTNAP2
googleCNTNAP2
gopubmedCNTNAP2
EVSCNTNAP2
HEFalMpCNTNAP2
MyGene2CNTNAP2
23andMeCNTNAP2
# SNPs36
 Max MagnitudeChromosome positionSummary
rs10244837146,778,222
rs10246256147,857,715
rs10273775147,200,311
rs10500171147,183,313
rs1219084450148,147,542
rs1358075146,438,846
rs150447075146,115,955
rs17170356147,190,776
rs17181010146,425,696
rs172362392147,885,213
rs1922892147,879,319
rs2107856147,491,593
rs2141388147,492,648
rs2190004147,571,368
rs2214681148,005,600
rs2538958147,918,548
rs2538976147,888,727
rs2538991147,882,527
rs2708240147,880,445
rs27101022147,877,298
rs2710117147,904,680
rs34712024146,116,001
rs3981242680147,903,619
rs4431523147,900,074
rs4549702148,203,924
rs6464816147,529,799
rs7308802750148,383,882
rs7308802760147,485,934
rs7525508490147,300,239
rs759178147,878,020
rs77947452146,792,514
rs77991810146,351,738
rs7960523740147,132,507
rs796052388147,121,075
rs8025680146,262,151
rs851715147,829,814


CNTNAP2 is a gene on chromosome 7 encoding the contactin-associated protein-like 2, a member of the neurexin superfamily. SNPs in CNTNAP2 have been associated with increased susceptibility to autism spectrum disorders:

  • rs7794745, a common polymorphism
  • rs2710102, another common SNP, linked to delayed onset of speech
  • Several rare variants found primarily in families with only affected males [PMID 18179895]