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From SNPedia

Also known as 1461_1462insA, 25889_25890insA, and 488Frameshift.[PMID 16580902]

Nonfunctional (and quite rare) allele of CYP3A4.

Heterozygotes with one of CYP3A4*20 allele plus one functioning allele are intermediate metabolizers for drugs metabolized by CYP3A4, and can develop significantly higher plasma concentrations of such drugs.[PMID 16580902]

Needs dbSNP rs#.