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DYRK1B

From SNPedia

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Full namedual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
EntrezGene9149
PheGenI9149
VariationViewer9149
ClinVarDYRK1B
dbSNP9149
SADR9149
HugeNav9149
wikipediaDYRK1B
googleDYRK1B
gopubmedDYRK1B
EVSDYRK1B
HEFalMpDYRK1B
MyGene2DYRK1B
23andMeDYRK1B
UniProtQ9Y463
EnsemblENSG00000105204
OMIM604556
# SNPs2
 Max MagnitudeChromosome positionSummary
rs367643250439,830,443metabolic syndrome (type-2 diabetes, coronary artery disease, obesity)
rs587777380039,830,478

The DYRK1B gene on chromosome 19 encodes the enzyme Dual specificity tyrosine-phosphorylation-regulated kinase 1B.Wikipedia

Genome-wide association studies have linked SNPs in DYRK1B to type-2 diabetes and traits associated with metabolic syndrome, and more recently, several quite rare variants (in particular, rs367643250 and one SNP lacking a dbSNP rsid) have been directly linked to an inherited form of metabolic syndrome, with implications for drug development across diabetes, heart disease, and obesity.[PMID 24827035]