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Dopamine/all

From SNPedia


Dopamine synthesis[edit]

 On chromosomeChromosome positionIn geneSummary
rs2060762750,461,686DDC
rs2242041750,461,751DDC
rs3757472750,470,285DDC
rs11761683750,475,181DDC
Rs11761683(T;T)750,475,181DDCMigraine
rs201951824750,476,625DDC
rs11575461750,479,485DDC
rs12718541750,482,446DDC
Rs12718541(A;A)750,482,446DDCNicotine dependence
rs1451371750,485,353DDC
rs137853209750,495,369DDC
Rs137853209(T;T)750,495,369DDCcommon in clinvar
Rs137853212(G;G)750,499,201DDCcommon in clinvar
rs137853212750,499,201DDC
Rs137853208(C;C)750,504,025DDCcommon in clinvar
rs137853208750,504,025DDC
rs6592961750,505,192DDC
rs1470750750,508,950DDC
rs3735273750,529,166DDC
rs137853210750,529,339DDC
Rs137853210(A;A)750,529,339DDCcommon in clinvar
rs998850750,539,690DDC
RGPD2
rs137853207750,539,926DDC
DDC-AS1
Rs137853207(G;G)750,539,926DDC
DDC-AS1
common in clinvar
Rs137853211(C;C)750,539,958DDC
DDC-AS1
common in clinvar
rs137853211750,539,958DDC
DDC-AS1
rs7809234750,542,681DDC
DDC-AS1
rs6264750,544,037DDC
Rs6264(G;G)750,544,037DDCcommon in complete genomics
Rs2044859(T;T)750,544,864DDCMigraine
rs2044859750,544,864DDC
Rs11974297(G;G)750,550,562DDCMigraine
rs11974297750,550,562DDC
rs2329340750,552,531DDC
Rs2329340(T;T)750,552,531DDCM
rs1451375750,555,014DDC
rs921451750,555,587DDC
rs3837091750,561,043DDC
rs12540874750,597,225GRB10
 On chromosomeChromosome positionIn geneSummary
rs4366464112,143,569IGF2
IGF2-AS
INS-IGF2
rs1003483112,146,313IGF2
INS-IGF2
Rs1003483(G;T)112,146,313IGF2
INS-IGF2
rs1003484112,146,388IGF2
INS-IGF2
rs10770125112,147,784IGF2
INS-IGF2
rs3741211112,147,880IGF2
IGF2-AS
INS-IGF2
rs3741208112,148,544IGF2
INS-IGF2
rs3741205112,148,654IGF2
INS-IGF2
rs3741204112,148,678IGF2
IGF2-AS
INS-IGF2
rs1004446112,148,913IGF2
INS-IGF2
rs4320932112,150,371IGF2
INS-IGF2
Rs4320932(A;A)112,150,371IGF2
INS-IGF2
normal
Rs4320932(A;G)112,150,371IGF2
INS-IGF2
0.87x decreased risk for ovarian cancer
Rs4320932(G;G)112,150,371IGF2
INS-IGF2
0.74x decreased risk for ovarian cancer
rs7924316112,152,217INS-IGF2
rs3842727112,163,618TH
Rs45471299(C;C)112,164,339THcommon in clinvar
rs45471299112,164,339TH
rs2070762112,165,105TH
rs786204540112,165,284TH
rs11564717112,165,659TH
Rs121917762(C;C)112,165,727THcommon in clinvar
rs121917762112,165,727TH
Rs587776767(A;A)112,165,787THcommon in clinvar
rs587776767112,165,787TH
Rs121917765(G;G)112,166,544THcommon in clinvar
rs121917765112,166,544TH
Rs28934580(G;G)112,166,693THcommon in clinvar
Rs28934580(C;C)112,166,693TH
rs28934580112,166,693TH
Rs121917764(C;C)112,166,762THcommon in clinvar
rs121917764112,166,762TH
Rs28934581(A;A)112,166,995THcommon in clinvar
rs28934581112,166,995TH
rs121917763112,167,896TH
Rs121917763(T;T)112,167,896THcommon in clinvar
rs80338892112,167,905TH
Rs80338892(G;G)112,167,905THcommon in clinvar
rs11042950112,168,488TH
rs797045111112,169,679TH
Rs6356(G;G)112,169,721THcommon in clinvar
rs6356112,169,721TH
rs10770140112,172,367MIR4686
TH
rs10770141112,172,610MIR4686
TH
rs10840491112,173,160MIR4686
TH
rs6578993112,179,933TH
rs28934579112,189,379TH
Rs28934579(A;A)112,189,379TH
Rs28934579(T;T)112,189,379THcommon in complete genomics

Dopamine conversion[edit]

to norepinephrine[edit]

 On chromosomeChromosome positionIn geneSummary
rs16111149133,635,081DBH
rs16111159133,635,393DBH
Rs1611115(C;C)9133,635,393DBHnormal
Rs1611115(C;T)9133,635,393DBHnormal
Rs1611115(T;T)9133,635,393DBHsomewhat more associated with impulsiveness and adult ADHD
rs2676067609133,636,672DBH
Rs267606760(G;G)9133,636,672DBHcommon in clinvar
rs748534769133,636,712DBH
Rs74853476(T;T)9133,636,712DBHcommon in clinvar
rs30253829133,637,199DBH
Rs2007153(A;A)9133,638,697DBHdecreased risk of schizophrenia in limited study
Rs2007153(A;G)9133,638,697DBHnormal risk of schizophrenia in limited study
Rs2007153(G;G)9133,638,697DBHincreased risk of schizophrenia in limited study
rs20071539133,638,697DBH
rs775768409133,639,848DBH
Rs77576840(C;C)9133,639,848DBHcommon in clinvar
Rs1108580(A;A)9133,639,992DBHcommon in clinvar
rs11085809133,639,992DBH
rs8632252449133,642,337DBH
Rs5320(G;G)9133,642,351DBHcommon in complete genomics
rs53209133,642,351DBH
rs8632252459133,643,474DBH
Rs4531(G;G)9133,644,248DBHcommon on affy axiom data
rs45319133,644,248DBH
rs25191529133,644,512DBH
Rs267606761(G;G)9133,647,854DBHcommon in clinvar
rs2676067619133,647,854DBH
rs752153319133,647,906DBH
Rs2283123(C;T)9133,650,175DBHdecreased risk of schizophrenia in limited study
Rs2283123(T;T)9133,650,175DBHdecreased risk of schizophrenia in limited study
rs22831239133,650,175DBH
Rs2283123(C;C)9133,650,175DBHnormal risk of schizophrenia in limited study
rs7393989133,651,448DBH
rs779059133,652,975DBH
rs62719133,657,152DBH
DBH-AS1
rs8632252469133,657,174DBH
DBH-AS1
rs1298829133,658,547DBH
DBH-AS1

Dopamine degradation[edit]

 On chromosomeChromosome positionIn geneSummary
rs20755072219,940,569COMT
TXNRD2
rs20976032219,940,569COMT
TXNRD2
rs20209172219,941,361COMT
TXNRD2
rs7378662219,942,586COMT
TXNRD2
Rs737865(A;G)2219,942,598COMT
TXNRD2
rs7378652219,942,598COMT
TXNRD2
rs9332712219,943,884COMT
rs59938822219,950,010COMT
rs30878692219,953,984COMT
rs7406032219,957,654COMT
rs46463122219,960,814COMT
rs1656562219,961,340COMT
rs1657222219,961,490COMT
rs62692219,962,429COMT
MIR4761
Rs4633(T;T)2219,962,712COMT
MIR4761
higher risk for endometrial cancer
Rs4633(C;T)2219,962,712COMT
MIR4761
higher risk for endometrial cancer
rs46332219,962,712COMT
MIR4761
Rs4633(C;C)2219,962,712COMT
MIR4761
normal
Rs6267(G;G)2219,962,740COMT
MIR4761
common
Rs6267(G;T)2219,962,740COMT
MIR4761
None
Rs6267(T;T)2219,962,740COMT
MIR4761
None
rs62672219,962,740COMT
MIR4761
Rs740602(G;G)2219,962,745COMT
MIR4761
common in complete genomics
rs7406022219,962,745COMT
MIR4761
rs22393932219,962,905COMT
MIR4761
Rs4818(C;G)2219,963,684COMT
MIR4761
rs48182219,963,684COMT
MIR4761
Rs8192488(C;C)2219,963,714COMT
MIR4761
common in complete genomics
rs81924882219,963,714COMT
MIR4761
rs46802219,963,748COMT
MIR4761
warrior vs worrier; number of other associations
rs1656882219,963,748COMT
MIR4761
Rs4680(A;G)2219,963,748COMT
MIR4761
multiple associations, see details
Rs165688(G;G)2219,963,748COMT
MIR4761
Rs4680(G;G)2219,963,748COMT
MIR4761
(warrior) multiple associations, see details
rs178493082219,963,748COMT
MIR4761
rs4680(A;A)2219,963,748COMT
MIR4761
(worrier) advantage in memory and attention tasks
rs7692242219,964,281COMT
MIR4761
Rs769224(G;G)2219,964,281COMT
MIR4761
rs46463162219,964,609COMT
rs1657742219,965,038COMT
Rs9332377(C;C)2219,968,169COMT
ARVCF
rs93323772219,968,169COMT
ARVCF
Rs165599(G;G)2219,969,258COMT
ARVCF
May indicate increased susceptibility to schizophrenia
rs1655992219,969,258COMT
ARVCF
Rs165599(A;G)2219,969,258COMT
ARVCF
Rs165599(A;A)2219,969,258COMT
ARVCF
 On chromosomeChromosome positionIn geneSummary
rs5953210X43,654,798MAOA
rs5906883X43,667,695MAOA
rs1465107X43,678,769MAOA
rs796065312X43,683,572MAOA
rs5906957X43,688,062MAOA
rs909525X43,693,955MAOABest proxy for Warrior Gene repeats.
Rs909525(A;A)X43,693,955MAOAProbably MAOA 4 or 5 repeats: not Warrior Gene.
Rs909525(G;G)X43,693,955MAOAPerhaps MAOA 3 repeats: Warrior Gene?
Rs909525(A;G)X43,693,955MAOAProbably one Warrior Gene and one non-Warrior Gene.
rs2283725X43,700,729MAOA
rs796065311X43,731,344MAOA
rs587777457X43,731,695MAOA
Rs587777457(G;G)X43,731,695MAOAcommon in clinvar
Rs72554632(C;C)X43,731,784MAOAcommon in clinvar
Rs72554632(C;T)X43,731,784MAOACarrier for Brunner's Syndrome
Rs72554632(T;T)X43,731,784MAOApossible mental retardation
rs72554632X43,731,784MAOA
Rs6323(T;T)X43,731,789MAOAreduced MAOA activity
rs6323X43,731,789MAOAMonoamine oxidase A activity
Rs6323(G;G)X43,731,789MAOAIncreased monoamine oxidase A activity
rs3027400X43,733,516MAOA
rs2235186X43,736,181MAOA
rs2072743X43,740,274MAOA
rs979606X43,741,895MAOA
rs1137070X43,744,144MAOA
rs3027407X43,745,594MAOA
rs3027409X43,747,786MAOA
Rs3027409(T;T)X43,747,786MAOAcommon on affy axiom data
rs6609257X43,753,461MAOA
 On chromosomeChromosome positionIn geneSummary
Rs3027415(T;T)X43,755,194MAOB
rs3027415X43,755,194MAOB
rs1799836X43,768,752MAOB
Rs1799836(C;C)X43,768,752MAOB
rs10521432X43,774,493MAOB
rs2283729X43,818,795MAOB
rs6651806X43,829,718MAOB

Dopamine transporters[edit]

 On chromosomeChromosome positionIn geneSummary
rs386314551,392,596SLC6A3
rs2836317051,393,747SLC6A3
Rs28363170(-;-)51,393,747SLC6A3
Rs27072(T;T)51,394,407SLC6A3Lower risk of alcohol withdrawal seizures, and probably lower odds of ADHD.
Rs27072(C;T)51,394,407SLC6A3Lower risk of alcohol withdrawal seizures, and perhaps lower odds of ADHD.
Rs27072(C;C)51,394,407SLC6A32x risk of severe alcohol withdrawal. Possible increased odds of ADHD.
rs2707251,394,407SLC6A3Associated with increased susceptibility to alcohol withdrawal symptoms and ADHD.
rs4018451,394,962SLC6A3
Rs6869645(C;C)51,404,433SLC6A3common in complete genomics
rs686964551,404,433SLC6A3
Rs431905516(C;C)51,406,226SLC6A3common in clinvar
rs43190551651,406,226SLC6A3
rs43190550451,411,242SLC6A3
Rs431905504(G;G)51,411,242SLC6A3common in clinvar
rs634751,411,297SLC6A3
Rs6347(A;A)51,411,297SLC6A3common in clinvar
Rs267607069(C;C)51,411,328SLC6A3common in clinvar
rs26760706951,411,328SLC6A3
rs383679051,411,740SLC6A3
Rs3836790(-;-)51,411,740SLC6A3common in complete genomics
Rs27048(T;T)51,412,530SLC6A3normal
rs2704851,412,530SLC6A3
Rs27048(C;C)51,412,530SLC6A32x risk of severe alcohol withdrawal
Rs27048(C;T)51,412,530SLC6A3normal
rs26760706851,414,744SLC6A3
Rs267607068(T;T)51,414,744SLC6A3common in clinvar
Rs37022(T;T)51,415,514SLC6A3common in complete genomics
rs3702251,415,514SLC6A3
Rs431905514(G;G)51,416,097SLC6A3common in clinvar
rs43190551451,416,097SLC6A3
rs43190551551,421,997SLC6A3
Rs431905515(T;T)51,421,997SLC6A3common in clinvar
rs46404951,423,790SLC6A3
Rs464049(C;C)51,423,790SLC6A3decreased risk of schizophrenia in limited study
Rs464049(C;T)51,423,790SLC6A3increased risk of schizophrenia in limited study
Rs464049(T;T)51,423,790SLC6A3increased risk of schizophrenia in limited study
rs1005201651,427,996SLC6A3
rs46337951,431,049SLC6A3
rs46000051,432,710SLC6A3
Rs460000(C;C)51,432,710SLC6A3Better response to amphetamine
rs497564651,433,286SLC6A3
Rs403636(G;G)51,438,239SLC6A3common in complete genomics
rs40363651,438,239SLC6A3
rs635051,443,084SLC6A3
Rs6350(C;C)51,443,084SLC6A3
rs293763951,443,613SLC6A3
rs296323851,444,312SLC6A3
rs297522651,445,501SLC6A3
rs265251151,446,274SLC6A3
rs261759651,446,604SLC6A3
... further results
 On chromosomeChromosome positionIn geneSummary
rs6091214310117,241,017SLC18A2
rs36338710117,244,053SLC18A2
Rs363387(T;T)10117,244,053SLC18A2
rs201558610117,262,226SLC18A2
rs36322410117,263,062SLC18A2
rs36322710117,267,055SLC18A2
rs36327610117,274,298SLC18A2

Dopamine receptors[edit]

D1-like[edit]

 On chromosomeChromosome positionIn geneSummary
rs117466415175,439,088DRD1
rs117496765175,439,295DRD1
Rs686(G;G)5175,441,697DRD1
rs6865175,441,697DRD1
Rs155417(C;C)5175,441,837DRD1common in complete genomics
rs1554175175,441,837DRD1
Rs1799914(G;G)5175,442,902DRD1common in complete genomics
rs17999145175,442,902DRD1
rs45325175,443,147DRD1
Rs4532(C;C)5175,443,147DRD1
rs53265175,443,193DRD1
Rs5326(A;G)5175,443,193DRD1possible psychiatric risks
rs2659815175,443,899DRD1
Rs265981(A;A)5175,443,899DRD1
 On chromosomeChromosome positionIn geneSummary
rs196755049,783,641DRD5
rs222785249,784,365DRD5
Rs2227852(A;A)49,784,365DRD5
Rs2227852(G;G)49,784,365DRD5common for caucasians, despite hapmap

D2-like[edit]

 On chromosomeChromosome positionIn geneSummary
rs223468911113,407,761DRD2
rs155492911113,408,042DRD2
rs224259211113,408,708DRD2
rs273484211113,409,552DRD2
rs627911113,410,351DRD2
rs627611113,410,675DRD2
rs273484111113,411,054DRD2
rs112449311113,411,573DRD2
Rs6277(C;C)11113,412,737DRD21.6x higher schizophrenia risk
Rs6277(C;T)11113,412,737DRD21.4x higher schizophrenia risk
rs627711113,412,737DRD2
Rs6277(T;T)11113,412,737DRD2normal schizophrenia risk, learns NoGo faster
rs627511113,412,755DRD2
Rs1801028(G;G)11113,412,762DRD2normal risk
rs180102811113,412,762DRD2
Rs1801028(C;G)11113,412,762DRD21.4x risk for schizophrenia
Rs1801028(C;C)11113,412,762DRD2normal risk
rs180049611113,412,766DRD2
Rs1800496(C;C)11113,412,766DRD2common in complete genomics
rs107656011113,412,966DRD2
Rs1076560(A;A)11113,412,966DRD2influences working memory
Rs1076560(A;C)11113,412,966DRD21.3x increased risk for alcoholism
Rs1076560(C;C)11113,412,966DRD2normal
rs228326511113,414,814DRD2
rs1236312511113,415,194DRD2
rs273483911113,415,768DRD2
Rs104894220(G;G)11113,416,935DRD2common in clinvar
rs10489422011113,416,935DRD2
rs107972711113,418,460DRD2
rs180049811113,420,866DRD2
rs207565211113,424,176DRD2
rs107656211113,425,286DRD2
rs107959811113,425,552DRD2
rs107959711113,425,564DRD2
rs107959611113,425,897DRD2
rs112539411113,426,463DRD2
rs443657811113,436,043DRD2
rs1121460611113,439,147DRD2
Rs11214606(C;C)11113,439,147DRD2common on affy axiom data
rs464831811113,442,667DRD2
rs464831911113,443,641DRD2
rs1760161211113,447,023DRD2
rs713105611113,459,052DRD2
Rs4648317(T;T)11113,460,810DRD2prone to higher nicotine dependence, more impulsive/sensation seeking
Rs4648317(C;C)11113,460,810DRD2normal
rs464831711113,460,810DRD2
Rs4648317(C;T)11113,460,810DRD2prone to higher nicotine dependence?
rs1121461311113,464,537DRD2
Rs11214613(G;G)11113,464,537DRD2common in complete genomics
rs493801911113,470,669DRD2
... further results
 On chromosomeChromosome positionIn geneSummary
rs46469963114,130,718DRD3
rs21346553114,139,354DRD3
rs22511773114,139,503DRD3
rs2012520873114,142,742DRD3
rs9634683114,144,040DRD3
rs37736793114,150,488DRD3
rs37736783114,151,231DRD3
rs26303493114,154,525DRD3
Rs2630349(G;G)3114,154,525DRD3common in complete genomics
rs26303513114,156,212DRD3
Rs2630351(G;G)3114,156,212DRD3common in complete genomics
Rs167771(A;A)3114,157,428DRD3
rs1677713114,157,428DRD3
Rs167771(G;G)3114,157,428DRD3
rs3240323114,158,981DRD3
Rs324032(A;A)3114,158,981DRD3common in complete genomics
rs1677703114,160,715DRD3
rs3240293114,162,776DRD3
rs37327833114,171,942DRD3
rs62803114,171,968DRD3
Rs6280(C;T)3114,171,968DRD3normal
Rs6280(C;C)3114,171,968DRD3better response to olanzapine
Rs6280(T;T)3114,171,968DRD3normal
rs98255633114,181,373DRD3
rs76207543114,229,128DRD3
rs9055683114,232,449DRD3
 On chromosomeChromosome positionIn geneSummary
rs375865311636,399DRD4
rs74730211636,689DRD4
rs93646211636,690DRD4
rs180095511636,784DRD4influences personality
Rs1800955(C;T)11636,784DRD4increased susceptibility to novelty seeking
Rs1800955(C;C)11636,784DRD4increased susceptibility to novelty seeking
Rs1800955(T;T)11636,784DRD4normal
Rs916457(C;C)11637,014DRD4
rs91645711637,014DRD4
rs55437571311637,537DRD4
rs58777684211637,539DRD4
Rs587776842(CCGCCGACCTCCT;CCGCCGACCTCCT)11637,539DRD4common in clinvar
rs75230611637,622DRD4
rs1272039011637,932DRD4
rs1272040311639,274DRD4
rs180044311639,830DRD4
Rs1800443(G;T)11639,830DRD4Uncommon DRD4 polymorphism
Rs1800443(G;G)11639,830DRD4Rare DRD4 polymorphism
Rs1800443(T;T)11639,830DRD4common in clinvar
rs76250211640,119DRD4
rs1272041011640,254DRD4
rs93646311640,432DRD4
Rs11246226(C;C)11641,191DRD4decreased risk of schizophrenia in limited study
Rs11246226(A;A)11641,191DRD4increased risk of schizophrenia in limited study
rs1124622611641,191DRD4
Rs11246226(A;C)11641,191DRD4decreased risk of schizophrenia in limited study
rs433114511643,683DRD4
Rs4331145(A;A)11643,683DRD4increased risk of schizophrenia in limited study
Rs4331145(A;G)11643,683DRD4decreased risk of schizophrenia in limited study
Rs4331145(G;G)11643,683DRD4increased risk of schizophrenia in limited study