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FECH

From SNPedia

is agene
is mentioned by
Full nameferrochelatase
EntrezGene2235
PheGenI2235
VariationViewer2235
ClinVarFECH
GeneCardsFECH
dbSNP2235
SADR2235
HugeNav2235
wikipediaFECH
googleFECH
gopubmedFECH
EVSFECH
HEFalMpFECH
MyGene2FECH
23andMeFECH
UniProtP22830
OMIM612386
# SNPs19
 Max MagnitudeChromosome positionSummary
rs1041951057,573,273
rs118204037057,559,148
rs118204039057,550,734
rs118204040057,551,367
rs146899669057,550,753
rs149067146057,573,244
rs202147607057,551,312
rs2269219057,580,222
rs2272783457,571,588
rs267606803057,550,760
rs267606804057,550,759
rs3848519457,580,104
rs397514476057,566,492
rs764466739057,551,316
rs786205245057,554,259
rs786205246057,573,240
rs786205247057,580,062
rs786205248057,566,461
rs879255507057,551,317

FECH codes for the ferrochelatase enzyme, nessasary for sythesizing heme. Defects cause Erythropoietic protoporphyria, a metabolic condition that causes photosensitivity.

FECH gene SNPs in SNPedia associated with erythropoietic protoporphyria, and the microarrays testing them when known, include:

SNP Rs# Common synonym On microarray?
rs3848519 GLY55CYS 23andMe v1, 23andMe v2, 23andMe v3, FTDNA2, FamilyTreeDNA, HumanOmni1Quad, Illumina Human 1M, 23andMe v4
rs118204037 MET267ILE
rs118204039 PHE417SER Ancestry v2
rs118204040 VAL363GLY Ancestry v2
rs267606804 ASN408LYS, PRO409SER, AND CYS411GLY Ancestry v2
rs2272783 IVS3AS, T-C, -48 23andMe v1, 23andMe v2, 23andMe v3, Affy GenomeWide 6, FTDNA2, HumanOmni1Quad, Illumina Human 1M, 23andMe v4, Ancestry v2
rs397514476 ALA185THR Ancestry v2
rs2269219 IVS1, C-T, -23 Ancestry v2
rs786205245 IVS9DS, G-A, +1
rs202147607 IVS10DS, A-G, +3 Ancestry v2
rs149067146 IVS3DS, T-G, +2
rs786205246 IVS3DS, A-C, +6
rs764466739 1-BP DEL, 1135A
rs786205247 IVS2DS, A-G, +11
rs786205248 5-BP DEL, NT580