Have questions? Visit https://www.reddit.com/r/SNPedia

GSTT1

From SNPedia

is agene
is mentioned by
Full nameglutathione S-transferase theta 1
RelatedGSTT2
EntrezGene2952
PheGenI2952
VariationViewer2952
ClinVarGSTT1
GeneCardsGSTT1
dbSNP2952
SADR2952
HugeNav2952
wikipediaGSTT1
googleGSTT1
gopubmedGSTT1
EVSGSTT1
HEFalMpGSTT1
MyGene2GSTT1
23andMeGSTT1
UniProtP30711
EnsemblENSG00000184674
OMIM600436
# SNPs3
 Max MagnitudeChromosome positionSummary
rs2266637024,376,845
rs463024,376,322
rs7174830924,376,618

Glutathione S-transferase (GST) theta 1 (GSTT1) is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds.

While testing for null alleles in GSTM1 seems sufficient for Caucasians and Oriental subjects, the most promising target SNPs for GSTT1 association studies in African-American and Hispanic subjects may be those causing the amino acid changes Asp43Asn, Thr65Met, Thr104Pro and the single nucleotide deletion in exon 4. [PMID 18303971]