Genos offers next-generation sequencing services to consumers. Based in San Francisco, Genos Research is a spin-off of Complete Genomics' consumer division and was founded in 2016 by two former executives of that company.
Genos is currently (as of August 2016) offering their exome sequencing service as a beta program with CLIA certified, 75x whole exome sequencing available for $399. This service includes:
- the ability to download your data; however, note that currently the only export format is not Promethease compatible;
- interactive tools, including a browsable map of your genetic variations and personalized variant and conditions summary; and,
- access to certified genetic counselors at preferred rates.
An option to download a Promethease-compatible file is expected to become available by or in November 2016. The "VCF" format used by Genos is not Promethease compatible and is not recommended for use.
Two major differences between Genos and other consumer genomics companies are the focus on next generation sequencing, and, the amount of data sequenced. Genos currently sequences an individual’s entire exome, covering ~50 million base pairs, compared to the ~1 million or less typical of microarray based providers.
Initial Promethease reports run with data provided by Genos yield ~42,000 genotypes, of which 34,000 are from ClinVar. By comparison, the most recent Ancestry ($99) and 23andMe ($199) based Promethease reports yield ~47,000 and 23,000 genotypes, with about 24,000 and 2,000 annotated in ClinVar, respectively.
A Genos core principle is that users own and control their own data and that it is never shared without their consent. Genos has said that starting in late 2016 it will enable users to share data with research partners on a study-by-study basis and to provide compensation (to users) for such sharing.
For more information about Genos Beta, visit URL: https://www.genosresearch.com/?cid=snp-100-ent.
Note: SNPedia and Promethease are not affiliated with Genos Research, and we receive no compensation from Genos Research (or any other DTC genomics companies, for that matter). Using the link to Genos Beta shown above allows Genos Beta to know that a visitor has come to them from SNPedia or Promethease.