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Gs141

From SNPedia

Gs141
Magnitude 3.5
Repute Bad
Summary 2x risk of Alzheimer's disease
Criteria Gs141/criteria


You carry one APOE-ε3 allele and one APOE-ε4 allele. This results in 2x increased relative risk of Alzheimer's disease. For non-caucasians the risk is increased, but SNPedia has not yet seen any reliable estimates.

This is based on

Community[edit]

Learning while you are healthy that your odds of developing Alzheimer's may be higher than average by the time you are 80 years old can be a shock. Some of the people who have learned about their higher risk have formed ApoE4.info, a non-profit for ApoE4 carriers to discuss research and provide support. This includes a research wiki and a discussion forum.

Genoset gs216 identifies carriers of two ApoE-ε4 alleles.