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Gs153

From SNPedia

Gs153
Magnitude 3.3
Repute
Summary CYP2C19 Extensive or Ultra-Fast Metabolizer
Criteria Gs153/criteria
CYP2C19 Ultra-rapid metabolizer. Your body breaks down (i.e., detoxifies) certain medicines more quickly. It is possible that you may need a higher than average dosage of the medicines metabolized by CYP2C19 in order for them to be effective.

Medicines metabolized by CYP2C19 include the following:

  • some hormones (such as estrogens and progesterone)
  • anti-epileptics (such as diazepam, phenytoin, and phenobarbitone),
  • anti-depressants (such as amitriptyline and clomipramine)
  • Clopidogrel Plavix Prilosec Nexium Prevacid