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Gs277

From SNPedia

Gs277
Magnitude 2.5
Repute Bad
Summary Increased risk of Atrial Fibrillation in one of the 2 SNPs mentioned by 23andMe.
Criteria Gs277/criteria


The more important of the two atrial fibrillation SNPs mentioned by 23andMe has one defective copy. This slightly affects the formation of the heart and increases risk of Atrial Fibrillation (quivering of the top part of the heart) that 23andMe reports. It also seems to increase the risk of Cardioembolic ischemic stroke (blocked blood flow to the brain) although 23andMe doesn't mention that. The risk is highest for men. Based on several quality studies, and confirmed for Europeans and Asians. It's recommended to eat a heart-healthy diet, and only drink alcohol in moderation, to lower the risk.