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HLA-C

From SNPedia

is agene
is mentioned by
Full namemajor histocompatibility complex, class I, C
EntrezGene3107
PheGenI3107
VariationViewer3107
ClinVarHLA-C
GeneCardsHLA-C
dbSNP3107
SADR3107
HugeNav3107
wikipediaHLA-C
googleHLA-C
gopubmedHLA-C
EVSHLA-C
HEFalMpHLA-C
MyGene2HLA-C
23andMeHLA-C
UniProtP10321
EnsemblENSG00000204525
OMIM142840
# SNPs528
 Max MagnitudeChromosome positionSummary
rs1049650031,269,031
rs1049663031,269,036
rs1049668031,269,044
rs1049709031,269,077
rs1049724031,269,085
rs1049853031,269,123
rs1050105031,269,992
rs1050106031,269,994
rs1050118031,269,999
rs1050147031,270,025
rs1050180031,270,056
rs1050276031,270,291
rs1050317031,270,358
rs1050320031,270,361
rs1050326031,270,370
rs1050328031,270,378
rs1050343031,270,455
rs1050344031,270,457
rs1050357031,271,103
rs1050366031,271,180
rs1050371031,271,233
rs1050373031,271,239
rs1050384031,271,305
rs1050685031,271,133
rs1050686031,271,132
rs1050716031,270,453
rs1065406031,271,272
rs1065600031,270,058
rs1065711031,269,076
rs1071649031,271,337
rs1130838031,269,347
rs1130935031,269,990
rs1130947031,269,996
rs1131014031,270,232
rs1131015031,270,233
rs1131096031,270,482
rs1131103031,271,091
rs1131104031,271,098
rs1131114031,271,323
rs1131115031,271,324
rs1131118031,271,331
rs1131119031,271,339
rs1131122031,271,599
rs1131123031,271,601
rs1131292031,270,469
rs114343571031,270,788
rs1143551031,269,983
rs11547346031,271,569
rs11547350031,271,191
rs11547351031,271,646
... further results


HLA-C(PSORS1), a gene/antigen member of the HLA family is associated with immune conditions. Over 300 alleles have been documented, with 44 common.

Variants are correlated with susceptibility to Psoriasis (HLA-Cw6 interaction with CDSN*TTC) and HIV (-35C-T, rs9264942).

HLA-C1 interaction with KIR2DL2 affects HSV-1 susceptibility.

HLA-C*05 may protect against MS.

Tag SNPs for HLA-C antitypes on the 1M Illumina chip[edit]

HLA SNP r2 HLA_FRQ SNP_FRQ
C*02:06 rs3093671 0.006 0.000 0.03
C*03:05 rs3093561 0.003 0.000 0.01
C*03:06 rs2517490 0.007 0.000 0.02
C*04:03 rs2269713 0.039 0.003 0.04
C*04:04 rs2074475 0.006 0.000 0.02
C*04:07 rs7774197 0.003 0.000 0.05
C*04:10 rs3819284 0.010 0.000 0.02
C*06:02 rs10484554 0.11
C*07:26 rs9296020 0.009 0.000 0.01
C*08:01 rs2524083 0.071 0.010 0.12
C*12:04 rs28732150 0.015 0.001 0.05
C*15:04 rs16899178 0.031 0.002 0.05
C*16:04 rs7747738 0.059 0.002 0.03
C*18:01 rs7759127 0.015 0.002 0.12