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From SNPedia

Hypercholesterolemia refers to high levels of cholesterol in the blood. This condition can contribute to many forms of disease, most notably cardiovascular disease Wikipedia.

SNPs that may play a role in hypercholesterolemia include:

Familial hypercholesterolemia (FH) is an inherited condition often caused by mutations in the low-density lipoprotein receptor (LDLR) gene (Wikipedia). About 1 in 500 people carries a mutation that can cause FH, but not all carriers develop symptoms. Such mutations are more common in some ethnic groups, such as people with French-Canadian ancestry. These OMIM entries discusses various forms of FH: