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IL4

From SNPedia

is agene
is mentioned by
Full nameinterleukin 4
EntrezGene3565
PheGenI3565
VariationViewer3565
ClinVarIL4
GeneCardsIL4
dbSNP3565
SADR3565
HugeNav3565
wikipediaIL4
googleIL4
gopubmedIL4
EVSIL4
HEFalMpIL4
MyGene2IL4
23andMeIL4
UniProtP05112
EnsemblENSG00000113520
OMIM147780
# SNPs11
 Max MagnitudeChromosome positionSummary
rs20708740132,674,018
rs2227284132,677,033
rs22432480132,672,952
rs22432502132,673,462
rs2243266132,678,097
rs2243267132,678,194
rs2243268132,678,271
rs2243270132,678,417
rs2243274132,679,140
rs2243289132,682,440
rs2243290132,682,477

The IL4 gene encodes interleukin 4, a cytokine that induces differentiation of naive helper T cells (Th0 cells) to Th2 cells. Upon activation by IL4, Th2 cells subsequently produce additional IL4 in a positive feedback loop. It is closely related and has functions similar to IL13 (Interleukin 13).