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Magnitude

From SNPedia

See also Max Magnitude, Genotype, Genoset and Repute and Promethease/Learn_More

Magnitude is a subjective measure of interest. Over time it should be adjusted up or down by the community. It is generally interpreted as follows...

0 You have the common genotype, for which nothing interesting is known.
0.1 You have the common genotype, but its interesting that this varies for others
1 Semi-plausible but not very exciting
(blank) No one has yet assigned a magnitude. Treated as a 1.
2 looks interesting enough to be worth reading
2.1 hmm, interesting
3 Probably worth your time
10 Really significant information!

Numbers bigger than 10 are allowed and expected in the future. Since User:Watson and User:Steven Pinker requested not to learn their APOE4 gs216 status that serves as useful a landmark in the scale. Several rare genotypes are higher magnitude. The genotypes with highest magnitude are

 MagnitudeReputeSummary
i4000378(I;I)10BadBRCA1 (breast cancer) 5382insC
rs587777465(C;C)9BadPontocerebellar hypoplasia type 2E
rs587777466(T;T)9BadPontocerebellar hypoplasia type 2E
rs773876739(C;C)9BadPontocerebellar hypoplasia type 2D
rs267607036(G;G)9BadPontocerebellar hypoplasia type 2D
rs267607035(A;A)9BadPontocerebellar hypoplasia type 2D
rs779709646(T;T)9BadSmith-Lemli-Opitz syndrome
rs770374710(-;G)9BadPrader-Willi-like syndrome; Schaaf-Yang syndrome
rs398122418(C;T)9BadPrader-Willi-like syndrome; Schaaf-Yang syndrome
rs398122417(-;AT)9BadPrader-Willi-like syndrome; Schaaf-Yang syndrome
... further results

The genosets with the highest magnitude are

 MagnitudeReputeSummary
Gs3037WeGene quality control issues.
Gs3007Data Quality issue. Your data provider is reporting heterozygosity on the Y chromosome.
Gs2286Badsickle cell affected
Gs2676APOE1/APOE1
Gs2166Bad2 copies of the APO-ε4 allele
Gs1215BadDR3/4-DQ8 individual at high risk for type-1 diabetes
Gs2615Did you mix multiple people together?
Gs2665Data Quality Warning
Gs2544.1BadPseudocholinesterase Deficiency
Gs2454Bad4x increased risk for esophageal squamous cell cancer among Han Chinese
... further results

See also the related concept Repute.