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NOS1

From SNPedia

is agene
is mentioned by
Full namenitric oxide synthase 1 (neuronal)
RelatedNOS1AP, NOS2, NOS3
EntrezGene4842
PheGenI4842
VariationViewer4842
ClinVarNOS1
GeneCardsNOS1
dbSNP4842
SADR4842
HugeNav4842
wikipediaNOS1
googleNOS1
gopubmedNOS1
EVSNOS1
HEFalMpNOS1
MyGene2NOS1
23andMeNOS1
UniProtP29475
EnsemblENSG00000089250
OMIM163731
# SNPs21
 Max MagnitudeChromosome positionSummary
rs1004356117,339,567
rs10507279117,342,469
rs11611788117,300,571
rs1483757117,323,735
rs1520811117,327,262
rs1879417117,365,710
rs2139733117,288,937
rs2293050117,281,017
rs2682826117,215,033
rs37822060117,307,284
rs3782218117,333,706
rs3782219117,350,435
rs3782221117,358,076
rs412791040117,439,680
rs478597117,313,620
rs561712117,314,264
rs6490121117,270,390
rs7308402117,321,642
rs7977109117,292,535
rs9658281117,329,773
rs9658490117,232,493

SNPs in the NOS1 gene, which is located on chromosome 12q, have been linked to restless legs syndrome. [PMID 18058820]

Examples of such SNPs include:

This finding may implicate the nitric oxide (NO)/arginine pathway in the development of restless legs syndrome, and thereby open the door to the use of NO modulating agents for its treatment. [PMID 18058820]