Pelvic organ prolapse
Pelvic organ prolapse is a very common condition, particularly among older women. It's estimated that half of all mothers will experience some form of prolapse in later life, but the actual number of affected women is unknown (due to under-reporting). Prolapse may also be called uterine prolapse, genital prolapse, uterovaginal prolapse, pelvic relaxation, pelvic floor dysfunction, urogenital prolapse or vaginal wall prolapse.
A familial tendency has been demonstrated in the etiology of pelvic organ prolapse (POP), and SNPs associated with increased risk are just starting to be reported. They include:
- rs1800255, in a member of the collagen gene family