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Arylsulfatase A pseudodeficiency

From SNPedia

At a minimum, these SNPs are known to be related, and others may also be

 Max Magnitude

Although arylsulfatase A pseudodeficiency is characterized as a disease, about 1-2% of any population of clinically healthy people have two copies of "the" ARSA pseudodeficiency allele, identified by rs6151429. This does lead to low levels of arylsulfatase (ARSA).[PMID 1678251OA-icon.png]

Other mutations in the ARSA gene lead to metachromatic leukodystrophy in a variety of forms.