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rs10012946

From SNPedia

Orientationplus
Stabilizedplus
Make rs10012946(C;C)
Make rs10012946(C;T)
Make rs10012946(T;T)
ReferenceGRCh38 38.1/141
Chromosome4
Position6291623
GeneWFS1
is asnp
is mentioned by
dbSNPrs10012946
ebirs10012946
HLIrs10012946
Exacrs10012946
Varsomers10012946
Maprs10012946
PheGenIrs10012946
hapmaprs10012946
1000 genomesrs10012946
hgdprs10012946
ensemblrs10012946
gopubmedrs10012946
geneviewrs10012946
scholarrs10012946
googlers10012946
pharmgkbrs10012946
gwascentralrs10012946
openSNPrs10012946
23andMers10012946
23andMe allrs10012946
SNP Nexus

SNPshotrs10012946
SNPdbers10012946
MSV3drs10012946
GWAS Ctlgrs10012946
GMAF0.2677
Max Magnitude
? (C;C) (C;T) (T;T) 28
Rs10012946
PubMed [PMID 17603484OA-icon.png]
Affy Probeset SNP_A-2232157
Affy Orientation same
On GW 5.0 1
Alleles A/B C/T
Ancestral T
Population Caucasian (UK)
Allele C
Case Freq.
Control Freq.
Odds Ratio Het
Odds Ratio Hom
Odds Ratio All 1.15
Disease Type II Diabetes (T2D)


rs10012946 is in linkage disequilibrium with a polymorphism that increases susceptibility to Type II Diabetes 1.15 times for carriers of the C allele [PMID 17603484OA-icon.png]

[PMID 18060660OA-icon.png] Testing of diabetes-associated WFS1 polymorphisms in the Diabetes Prevention Program.

[PMID 18426861OA-icon.png] Association analysis of type 2 diabetes Loci in type 1 diabetes.

[PMID 18694974OA-icon.png] Predicting type 2 diabetes based on polymorphisms from genome-wide association studies: a population-based study.

[PMID 19096518OA-icon.png] Novel association of HK1 with glycated hemoglobin in a non-diabetic population: a genome-wide evaluation of 14,618 participants in the Women's Genome Health Study.

[PMID 19341491OA-icon.png] Genome-based prediction of common diseases: methodological considerations for future research.

[PMID 20018041OA-icon.png] The effect of multiple genetic variants in predicting the risk of type 2 diabetes.