Have questions? Visit https://www.reddit.com/r/SNPedia

rs10036748

From SNPedia

Orientationplus
Stabilizedplus
Make rs10036748(C;C)
Make rs10036748(C;T)
Make rs10036748(T;T)
ReferenceGRCh38 38.1/141
Chromosome5
Position151078585
GeneTNIP1
is asnp
is mentioned by
dbSNPrs10036748
ebirs10036748
HLIrs10036748
Exacrs10036748
Varsomers10036748
Maprs10036748
PheGenIrs10036748
hapmaprs10036748
1000 genomesrs10036748
hgdprs10036748
ensemblrs10036748
gopubmedrs10036748
geneviewrs10036748
scholarrs10036748
googlers10036748
pharmgkbrs10036748
gwascentralrs10036748
openSNPrs10036748
23andMers10036748
23andMe allrs10036748
SNP Nexus

SNPshotrs10036748
SNPdbers10036748
MSV3drs10036748
GWAS Ctlgrs10036748
GMAF0.4555
Max Magnitude
? (C;C) (C;T) (T;T) 28
GWAS snp
PMID [PMID 19838193]
Trait Systemic lupus erythematosus
Title Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus
Risk Allele A
P-val 2E-9
Odds Ratio 1.23 [1.15-1.33]


[PMID 20516000] TNIP1, SLC15A4, ETS1, RasGRP3 and IKZF1 are associated with clinical features of systemic lupus erythematosus in Chinese Han population

OMIM152700
Desc
Variant
Relatedalso
OMIM152700
Desc
Variant
Relatedalso
OMIM152700
Desc
Variant
Relatedalso
[PMID 21379322OA-icon.png] Risk alleles for systemic lupus erythematosus in a large case-control collection and associations with clinical subphenotypes.

[PMID 21408207OA-icon.png] Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.


GET Evidence
rs10036748
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.507812
summary



GWAS snp
PMID [PMID 23273568OA-icon.png]
Trait Systemic lupus erythematosus
Title Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians.
Risk Allele T
P-val 3E-6
Odds Ratio 1.25


[PMID 22694930OA-icon.png] Genome-wide association studies of asthma indicate opposite immunopathogenesis direction from autoimmune diseases.