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rs1004446

From SNPedia

Orientationminus
Stabilizedplus
Make rs1004446(C;C)
Make rs1004446(C;T)
Make rs1004446(T;T)
ReferenceGRCh38 38.1/142
Chromosome11
Position2148913
GeneIGF2, INS-IGF2
is asnp
is mentioned by
dbSNPrs1004446
ebirs1004446
HLIrs1004446
Exacrs1004446
Varsomers1004446
Maprs1004446
PheGenIrs1004446
hapmaprs1004446
1000 genomesrs1004446
hgdprs1004446
ensemblrs1004446
gopubmedrs1004446
geneviewrs1004446
scholarrs1004446
googlers1004446
pharmgkbrs1004446
gwascentralrs1004446
openSNPrs1004446
23andMers1004446
23andMe allrs1004446
SNP Nexus

SNPshotrs1004446
SNPdbers1004446
MSV3drs1004446
GWAS Ctlgrs1004446
GMAF0.3462
Max Magnitude
? (C;C) (C;T) (T;T) 28
GWAS snp
PMID [PMID 17632545]
Trait Type 1 diabetes
Title A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene
Risk Allele C
P-val 4.0000000000000002E-9
Odds Ratio 1.61 [1.37-1.89]
GWAS snp
PMID [PMID 21829393OA-icon.png]
Trait
Title Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases.
Risk Allele G
P-val 3E-23
Odds Ratio 1.4000 [NR]


[PMID 17980034OA-icon.png] Cubic exact solutions for the estimation of pairwise haplotype frequencies: implications for linkage disequilibrium analyses and a web tool 'CubeX'.


[PMID 18647951OA-icon.png] A human type 1 diabetes susceptibility locus maps to chromosome 21q22.3.


[PMID 18840781OA-icon.png] Follow-up analysis of genome-wide association data identifies novel loci for type 1 diabetes.


[PMID 19136655OA-icon.png] Genome-wide scan for linkage to type 1 diabetes in 2,496 multiplex families from the Type 1 Diabetes Genetics Consortium.


[PMID 19732865OA-icon.png] A generalized family-based association test for dichotomous traits.


[PMID 19956101OA-icon.png] Overview of the Rapid Response data.


[PMID 19956106OA-icon.png] Analysis of 19 genes for association with type I diabetes in the Type I Diabetes Genetics Consortium families.


[PMID 21078522OA-icon.png] Common genetic variation within IGFI, IGFII, IGFBP-1, and IGFBP-3 and endometrial cancer risk.


GET Evidence
rs1004446
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.33871
summary



[PMID 24824313OA-icon.png] Insulin-like Growth Factor Pathway Genetic Polymorphisms, Circulating IGF1 and IGFBP3, and Prostate Cancer Survival


[PMID 25037061] Insulin-like Growth Factor Pathway Genetic Polymorphisms, Circulating IGF1 and IGFBP3, and Prostate Cancer Survival


[PMID 25117571OA-icon.png] Circulating IGF1 and IGF2 and SNP genotypes in pregnant and non-pregnant women and men