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rs1004467

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(T;T) 0
Make rs1004467(C;C)
Make rs1004467(C;T)
ReferenceGRCh38 38.1/142
Chromosome10
Position102834750
GeneCYP17A1, CYP17A1-AS1
is asnp
is mentioned by
dbSNPrs1004467
ebirs1004467
HLIrs1004467
Exacrs1004467
Varsomers1004467
Maprs1004467
PheGenIrs1004467
hapmaprs1004467
1000 genomesrs1004467
hgdprs1004467
ensemblrs1004467
gopubmedrs1004467
geneviewrs1004467
scholarrs1004467
googlers1004467
pharmgkbrs1004467
gwascentralrs1004467
openSNPrs1004467
23andMers1004467
23andMe allrs1004467
SNP Nexus

SNPshotrs1004467
SNPdbers1004467
MSV3drs1004467
GWAS Ctlgrs1004467
GMAF0.1993
Max Magnitude0
? (C;C) (C;T) (T;T) 28

23andMe blog blood pressure

GWAS snp
PMID [PMID 19430479OA-icon.png]
Trait Systolic blood pressure
Title Genome-wide association study of blood pressure and hypertension
Risk Allele A
P-val 1E-10
Odds Ratio 1.05 [0.74-1.36] mm Hg increase


[PMID 20921432] Common Variants in the ATP2B1 Gene Are Associated With Susceptibility to Hypertension. The Japanese Millennium Genome Project

[PMID 20852445] Common variants in or near FGF5, CYP17A1 and MTHFR genes are associated with blood pressure and hypertension in Chinese Hans.


GET Evidence
rs1004467
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.123257
summary



[PMID 23133444OA-icon.png] Genetic variation in CYP17A1 is associated with arterial stiffness in diabetic subjects


[PMID 22714708] Genetic polymorphisms of CYP17A1 in steroidogenesis pathway are associated with risk of progression to castration-resistant prostate cancer in Japanese men receiving androgen deprivation therapy.


[PMID 23102448] Physical activity modifies the associations between genetic variants and hypertension in the Chinese children.


[PMID 23591986] Influence of obesity on association between genetic variants identified by genome-wide association studies and hypertension risk in Chinese children.


[PMID 24671014] Genetic risk assessment for cardiovascular disease with seven genes associated with plasma C-reactive protein concentrations in Asian populations


[PMID 25917616] CYP17A1 and CYP2E1 Variants Associated with High Altitude Polycythemia in Tibetans at the Qinghai-Tibetan Plateau


[PMID 25990650] The relationship between the polymorphisms of the CYP17A1 gene and hypertension: A meta-analysis


[PMID 26263970OA-icon.png] A Single Nucleotide Polymorphism near the CYP17A1 Gene Is Associated with Left Ventricular Mass in Hypertensive Patients under Pharmacotherapy