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rs10086908

From SNPedia
(Redirected from Rs1006908)

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 2 1.7x increased risk for prostate cancer
(C;T) 2 1.7x increased risk for prostate cancer
(T;T) 0 normal risk
ReferenceGRCh38 38.1/141
Chromosome8
Position126999692
is asnp
is mentioned by
dbSNPrs10086908
ebirs10086908
HLIrs10086908
Exacrs10086908
Varsomers10086908
Maprs10086908
PheGenIrs10086908
hapmaprs10086908
1000 genomesrs10086908
hgdprs10086908
ensemblrs10086908
gopubmedrs10086908
geneviewrs10086908
scholarrs10086908
googlers10086908
pharmgkbrs10086908
gwascentralrs10086908
openSNPrs10086908
23andMers10086908
23andMe allrs10086908
SNP Nexus

SNPshotrs10086908
SNPdbers10086908
MSV3drs10086908
GWAS Ctlgrs10086908
GMAF0.2769
Max Magnitude2
? (C;C) (C;T) (T;T) 28
rs10086908 is a SNP in the 8q24 chromosomal region, which has been linked in several studies to prostate cancer.

In a study of 1,563 patients of European ancestry, rs10086908 was designated as the representative of a prostate cancer risk region termed "locus 3", with an odds ratio of 1.70 (CI: 1.39-2.07) for carriers of a risk genotype. Two other regions of chromosome 8q24 were also studied.[PMID 17925536]


[PMID 19549807OA-icon.png] Prostate Cancer Risk Associated Loci in African Americans


[PMID 19767752] Multiple loci on 8q24 associated with prostate cancer susceptibility


[PMID 21756274OA-icon.png] Systematic confirmation study of reported prostate cancer risk-associated single nucleotide polymorphisms in Chinese men

[PMID 17978284OA-icon.png] Confirmation study of prostate cancer risk variants at 8q24 in African Americans identifies a novel risk locus.

[PMID 18670647OA-icon.png] Homozygous deletions and recurrent amplifications implicate new genes involved in prostate cancer.


[PMID 23405784] [Susceptibility to prostate cancer in Han Chinese: single nucleotide polymorphism analysis of 1 667 cases]


[PMID 24779299] Study of genetic variants of 8q21 and 8q24 associated with prostate cancer in Jing-Jin residents in northern China