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rs10096633

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Orientationplus
Stabilizedplus
Make rs10096633(C;C)
Make rs10096633(C;T)
Make rs10096633(T;T)
ReferenceGRCh38 38.1/141
Chromosome8
Position19973410
is asnp
is mentioned by
dbSNPrs10096633
ebirs10096633
HLIrs10096633
Exacrs10096633
Varsomers10096633
Maprs10096633
PheGenIrs10096633
hapmaprs10096633
1000 genomesrs10096633
hgdprs10096633
ensemblrs10096633
gopubmedrs10096633
geneviewrs10096633
scholarrs10096633
googlers10096633
pharmgkbrs10096633
gwascentralrs10096633
openSNPrs10096633
23andMers10096633
23andMe allrs10096633
SNP Nexus

SNPshotrs10096633
SNPdbers10096633
MSV3drs10096633
GWAS Ctlgrs10096633
GMAF0.2071
Max Magnitude
? (C;C) (C;T) (T;T) 28
GWAS snp
PMID [PMID 19060911OA-icon.png]
Trait Triglycerides
Title Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts
Risk Allele G
P-val 2E-18
Odds Ratio 0.17 [NR] SD increase
GWAS snp
PMID [PMID 19060910OA-icon.png]
Trait Other metabolic traits
Title Genome-wide association analysis of metabolic traits in a birth cohort from a founder population
Risk Allele A
P-val 5E-8
Odds Ratio 0.12 [0.07-0.17] mmol/l decrease


OMIM609708
DescLIPOPROTEIN LIPASE; LPL
Variant
Relatedalso
[PMID 21252145OA-icon.png] Physical Activity Modifies the Effect of LPL, LIPC and CETP Polymorphisms on HDL-C Levels and the Risk of Myocardial Infarction in Caucasian Women


[PMID 18078817OA-icon.png] Multiple genetic determinants of plasma lipid levels in Caribbean Hispanics.


[PMID 19148283OA-icon.png] Genetic differences between the determinants of lipid profile phenotypes in African and European Americans: the Jackson Heart Study.


[PMID 19951432OA-icon.png] Analysis of recently identified dyslipidemia alleles reveals two loci that contribute to risk for carotid artery disease.


[PMID 20160193OA-icon.png] Investigation of variants identified in caucasian genome-wide association studies for plasma high-density lipoprotein cholesterol and triglycerides levels in Mexican dyslipidemic study samples.


[PMID 21347282OA-icon.png] Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.


GET Evidence
rs10096633
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.25
summary



GWAS snp
PMID [PMID 20139978]
Trait Triglycerides
Title Genome-wide association study of hematological and biochemical traits in a Japanese population.
Risk Allele T
P-val 9E-14
Odds Ratio .17 [0.12-0.21] unit decrease