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rs10168266

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) normal risk of Sjogren's syndrome
(C;T) 1.44x risk of Sjogren's syndrome
(T;T) 1.44x risk of Sjogren's syndrome
ReferenceGRCh38 38.1/141
Chromosome2
Position191071078
GeneSTAT4
is asnp
is mentioned by
dbSNPrs10168266
ebirs10168266
HLIrs10168266
Exacrs10168266
Varsomers10168266
Maprs10168266
PheGenIrs10168266
hapmaprs10168266
1000 genomesrs10168266
hgdprs10168266
ensemblrs10168266
gopubmedrs10168266
geneviewrs10168266
scholarrs10168266
googlers10168266
pharmgkbrs10168266
gwascentralrs10168266
openSNPrs10168266
23andMers10168266
23andMe allrs10168266
SNP Nexus

SNPshotrs10168266
SNPdbers10168266
MSV3drs10168266
GWAS Ctlgrs10168266
GMAF0.2328
Max Magnitude
? (C;C) (C;T) (T;T) 28

[PMID 20176035] Association of signal transducer and activator of transcription 4 genetic variants with extra-intestinal manifestations in inflammatory bowel disease


[PMID 18516230OA-icon.png] Specificity of the STAT4 genetic association for severe disease manifestations of systemic lupus erythematosus.


[PMID 18579578OA-icon.png] A risk haplotype of STAT4 for systemic lupus erythematosus is over-expressed, correlates with anti-dsDNA and shows additive effects with two risk alleles of IRF5.


[PMID 18803832OA-icon.png] Role of STAT4 polymorphisms in systemic lupus erythematosus in a Japanese population: a case-control association study of the STAT1-STAT4 region.


[PMID 19333953OA-icon.png] High-density genotyping of STAT4 reveals multiple haplotypic associations with systemic lupus erythematosus in different racial groups.


[PMID 20169177OA-icon.png] Genome-wide association study in Asian populations identifies variants in ETS1 and WDFY4 associated with systemic lupus erythematosus.


[PMID 22569826] Abnormal Genetic and Epigenetic Changes in Signal Transducer and Activator of Transcription 4 in the Pathogenesis of Inflammatory Bowel Diseases.


[PMID 23755762OA-icon.png] STAT4 is a genetic risk factor for systemic sclerosis in a Chinese population

GWAS snp
PMID [PMID 24097066]
Trait Sjögren's syndrome
Title A genome-wide association study in Han Chinese identifies a susceptibility locus for primary Sjögren's syndrome at 7q11.23.
Risk Allele T
P-val 2E-17
Odds Ratio 1.44 [1.32-1.57]


[PMID 24741605OA-icon.png] Insight into gene polymorphisms involved in toll-like receptor/interferon signalling pathways for systemic lupus erythematosus in South East Asia