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rs1026732

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) 2 <0.70x risk for restless legs
(A;G) 1.5 0.70x risk for restless legs
(G;G) 1 normal risk of restless leg syndrome
ReferenceGRCh38 38.1/141
Chromosome15
Position67802747
GeneMAP2K5
is asnp
is mentioned by
dbSNPrs1026732
ebirs1026732
HLIrs1026732
Exacrs1026732
Varsomers1026732
Maprs1026732
PheGenIrs1026732
hapmaprs1026732
1000 genomesrs1026732
hgdprs1026732
ensemblrs1026732
gopubmedrs1026732
geneviewrs1026732
scholarrs1026732
googlers1026732
pharmgkbrs1026732
gwascentralrs1026732
openSNPrs1026732
23andMers1026732
23andMe allrs1026732
SNP Nexus

SNPshotrs1026732
SNPdbers1026732
MSV3drs1026732
GWAS Ctlgrs1026732
GMAF0.4913
Max Magnitude2
? (A;A) (A;G) (G;G) 28
rs1026732, a SNP located in a region of chromosome 15q, has been linked to a lower frequency of restless legs syndrome, a common sleep disorder, with an overall odds ratio of 0.70 (CI: 0.59-0.82) for the (A) minor allele. [PMID 17637780]



[PMID 19279021OA-icon.png] Replication of restless legs syndrome loci in three European populations.


[PMID 20396431OA-icon.png] Genotyping sleep disorders patients.


GET Evidence
rs1026732
aa_change
aa_change_short
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.468254
summary