Have questions? Visit https://www.reddit.com/r/SNPedia

rs1036145

From SNPedia

Orientationminus
Stabilizedminus
Make rs1036145(A;A)
Make rs1036145(A;G)
Make rs1036145(G;G)
ReferenceGRCh38 38.1/141
Chromosome7
Position150977342
GeneKCNH2
is asnp
is mentioned by
dbSNPrs1036145
ebirs1036145
HLIrs1036145
Exacrs1036145
Varsomers1036145
Maprs1036145
PheGenIrs1036145
hapmaprs1036145
1000 genomesrs1036145
hgdprs1036145
ensemblrs1036145
gopubmedrs1036145
geneviewrs1036145
scholarrs1036145
googlers1036145
pharmgkbrs1036145
gwascentralrs1036145
openSNPrs1036145
23andMers1036145
23andMe allrs1036145
SNP Nexus

SNPshotrs1036145
SNPdbers1036145
MSV3drs1036145
GWAS Ctlgrs1036145
GMAF0.2309
Max Magnitude
? (A;A) (A;G) (G;G) 28
g2b2mh (sourced from [PMID 19412172OA-icon.png]) rs3800779 rs748693 and rs1036145 are associated with a variety of brain parameters such as hippocampal volume, hippocampal activity (declarative memory task) and activity in the dorsolateral prefrontal cortex (DLPFC). The main suggestion of how these variants in KCNH2 might lead to these brain changes and risk for schizophrenia comes from previous findings that mutations in this gene screw up the efflux of K+ ions during the repolarization phase of an action potential.


[PMID 19490382] Genetic polymorphism of KCNH2 confers predisposition of acquired atrial fibrillation in Chinese.