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rs10380

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 0 common in complete genomics
Make rs10380(C;T)
Make rs10380(T;T)
ReferenceGRCh38 38.1/141
Chromosome5
Position7897078
GeneMTRR
is asnp
is mentioned by
dbSNPrs10380
dbSNP (classic)rs10380
ClinGenrs10380
ebirs10380
HLIrs10380
Exacrs10380
Gnomadrs10380
Varsomers10380
LitVarrs10380
Maprs10380
PheGenIrs10380
Biobankrs10380
1000 genomesrs10380
hgdprs10380
ensemblrs10380
geneviewrs10380
scholarrs10380
googlers10380
pharmgkbrs10380
gwascentralrs10380
openSNPrs10380
23andMers10380
SNPshotrs10380
SNPdbers10380
MSV3drs10380
GWAS Ctlgrs10380
GMAF0.1901
Max Magnitude0
? (C;C) (C;T) (T;T) 28


[PMID 18515090] pancreatic cancer 702 cases and 785 controls

  • rs162049 P = .0018; OR, 1.33; 95% CI: 1.11-1.60
  • rs10380 (His595Tyr) P = .0063; OR, 1.45; 95% CI: 1.11-1.88


[PMID 19493349OA-icon.png] 118 SNPs of folate-related genes and risks of spina bifida and conotruncal heart defects


[PMID 21211571] MTHFR and MTRR genotype and haplotype analysis and colorectal cancer susceptibility in a case-control study from the Czech Republic


[PMID 19064578OA-icon.png] No association of single nucleotide polymorphisms in one-carbon metabolism genes with prostate cancer risk.


[PMID 20445798OA-icon.png] Chromosome 5p Region SNPs Are Associated with Risk of NSCLC among Women.



[PMID 22957669OA-icon.png] Association of dietary and genetic factors related to one-carbon metabolism with global methylation level of leukocyte DNA


ClinVar
Risk rs10380(T;T)
Alt rs10380(T;T)
Reference Rs10380(C;C)
Significance Non-pathogenic
Disease not specified Gastrointestinal stromal tumor Disorders of Intracellular Cobalamin Metabolism
Variation info
Gene MTRR
CLNDBN not specified Gastrointestinal stromal tumor Disorders of Intracellular Cobalamin Metabolism
Reversed 0
HGVS NC_000005.9:g.7897191C>T
CLNSRC UniProtKB (protein)
CLNACC RCV000126880.2, RCV000144924.1, RCV000302798.1,