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rs10399805

From SNPedia

Orientationplus
Stabilizedplus
Make rs10399805(A;A)
Make rs10399805(A;G)
Make rs10399805(G;G)
ReferenceGRCh38 38.1/141
Chromosome1
Position203186870
GeneCHI3L1
is asnp
is mentioned by
dbSNPrs10399805
ebirs10399805
HLIrs10399805
Exacrs10399805
Varsomers10399805
Maprs10399805
PheGenIrs10399805
hapmaprs10399805
1000 genomesrs10399805
hgdprs10399805
ensemblrs10399805
gopubmedrs10399805
geneviewrs10399805
scholarrs10399805
googlers10399805
pharmgkbrs10399805
gwascentralrs10399805
openSNPrs10399805
23andMers10399805
23andMe allrs10399805
SNP Nexus

SNPshotrs10399805
SNPdbers10399805
MSV3drs10399805
GWAS Ctlgrs10399805
GMAF0.2778
Max Magnitude
? (A;A) (A;G) (G;G) 28
[PMID 18281018] schizophrenia
  • 375 case and 812 control subjects
  • rs10399805 p = .018 and rs2275351; p = .008.

[PMID 18767121] An attempt to repeat the association between rs10399805 and risk for schizophrenia in an ethnically identical population (Japanese) as well as a new population (Han Chinese) failed to show any significant association.

[PMID 19106306] rs10399805(T;T) genotype showed a 2.5-fold increase in CHI3L1 mRNA expression in peripheral blood cells than those with (C;C) which is associated with the risk of atopy.

Neighborrs4950928
Distance116


[PMID 20051317] The chitinase 3-like 1 gene and schizophrenia: Evidence from a multi-center case-control study and meta-analysis


[PMID 17160890OA-icon.png] Functional variants in the promoter region of Chitinase 3-like 1 (CHI3L1) and susceptibility to schizophrenia.


[PMID 18403759OA-icon.png] Effect of variation in CHI3L1 on serum YKL-40 level, risk of asthma, and lung function.


[PMID 19568425OA-icon.png] Association of polymorphisms of the CHI3L1 gene with asthma and atopy: a populations-based study of 6514 Danish adults.


[PMID 21257319] Genetic polymorphisms in chitinase 3-like 1 (CHI3L1) are associated with circulating YKL-40 levels, but not with angiographic coronary artery disease in a Chinese population.


GET Evidence
rs10399805
aa_change
aa_change_short
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.233871
summary



[PMID 25203433OA-icon.png] Correlation of Chitinase 3-Like 1 Single Nucleotide Polymorphisms and Haplotypes with Uterine Cervical Cancer in Taiwanese Women