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rs1042058

From SNPedia

Orientationplus
Stabilizedplus
Make rs1042058(C;C)
Make rs1042058(C;T)
Make rs1042058(T;T)
ReferenceGRCh38 38.1/142
Chromosome10
Position30439172
GeneMAP3K8
is asnp
is mentioned by
dbSNPrs1042058
ebirs1042058
HLIrs1042058
Exacrs1042058
Varsomers1042058
Maprs1042058
PheGenIrs1042058
hapmaprs1042058
1000 genomesrs1042058
hgdprs1042058
ensemblrs1042058
gopubmedrs1042058
geneviewrs1042058
scholarrs1042058
googlers1042058
pharmgkbrs1042058
gwascentralrs1042058
openSNPrs1042058
23andMers1042058
23andMe allrs1042058
SNP Nexus

SNPshotrs1042058
SNPdbers1042058
MSV3drs1042058
GWAS Ctlgrs1042058
GMAF0.4284
Max Magnitude
? (C;C) (C;T) (T;T) 28
GWAS snp
PMID [PMID 23128233OA-icon.png]
Trait Inflammatory bowel disease
Title Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.
Risk Allele C
P-val 6E-11
Odds Ratio 1.08 [1.044-1.106]


[PMID 18091754OA-icon.png] Regional association-based fine-mapping for sodium-lithium countertransport on chromosome 10.


[PMID 26215868] A TPL2 (MAP3K8) disease-risk polymorphism increases TPL2 expression thereby leading to increased pattern recognition receptor-initiated caspase-1 and caspase-8 activation, signalling and cytokine secretion