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rs1042778

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(T;T) 1.5 Slightly lower oxytocin & empathy? Possibly higher 'callous-unemotional' trait frequency in children.
Make rs1042778(G;G)
Make rs1042778(G;T)
ReferenceGRCh38 38.1/141
Chromosome3
Position8752859
GeneOXTR
is asnp
is mentioned by
dbSNPrs1042778
ebirs1042778
HLIrs1042778
Exacrs1042778
Varsomers1042778
Maprs1042778
PheGenIrs1042778
hapmaprs1042778
1000 genomesrs1042778
hgdprs1042778
ensemblrs1042778
gopubmedrs1042778
geneviewrs1042778
scholarrs1042778
googlers1042778
pharmgkbrs1042778
gwascentralrs1042778
openSNPrs1042778
23andMers1042778
23andMe allrs1042778
SNP Nexus

SNPshotrs1042778
SNPdbers1042778
MSV3drs1042778
GWAS Ctlgrs1042778
GMAF0.3655
Max Magnitude1.5
? (G;G) (G;T) (T;T) 28
blog rs1042778, rs2268490 and rs237887 in OXTR influence prosociality


[PMID 24059750] Polymorphisms in the oxytocin receptor gene are associated with the development of psychopathy. A study of ~120 children, followed by a replication in ~100 children, concluded that the rs1042778(T;T) genotype was associated with high levels of callous-unemotional (CU) traits in both samples.


[PMID 22357335] The association between oxytocin receptor gene polymorphism (OXTR) and trait empathy


[PMID 22421562] Associations between oxytocin receptor gene (OXTR) polymorphisms and self-reported aggressive behavior and anger: Interactions with alcohol consumption


[PMID 12444087] Protein 4.1N is required for translocation of inositol 1,4,5-trisphosphate receptor type 1 to the basolateral membrane domain in polarized Madin-Darby canine kidney cells.


[PMID 17668382OA-icon.png] Type 2 diabetes whole-genome association study in four populations: the DiaGen consortium.


[PMID 19461999OA-icon.png] The oxytocin receptor (OXTR) contributes to prosocial fund allocations in the dictator game and the social value orientations task.


[PMID 19943975OA-icon.png] Polymorphism in the oxytocin promoter region in patients with lactase non-persistence is not related to symptoms.


[PMID 20585395OA-icon.png] No association between oxytocin receptor (OXTR) gene polymorphisms and experimentally elicited social preferences.


[PMID 20587075OA-icon.png] Genetic evidence of multiple loci in dystocia--difficult labour.


[PMID 21484202OA-icon.png] Association of oxytocin receptor (OXTR) gene variants with multiple phenotype domains of autism spectrum disorder.


[PMID 22336563] Sensitive Parenting Is Associated with Plasma Oxytocin and Polymorphisms in the OXTR and CD38 Genes.


[PMID 22372486] The role of oxytocin and oxytocin receptor gene variants in childhood-onset aggression.


[PMID 23974948OA-icon.png] Cumulative Risk on the Oxytocin Receptor Gene (OXTR) Underpins Empathic Communication Difficulties at the First Stages of Romantic Love


[PMID 24485285OA-icon.png] Association between the oxytocin receptor (OXTR) gene and mesolimbic responses to rewards


[PMID 23325323OA-icon.png] Parental oxytocin and early caregiving jointly shape children's oxytocin response and social reciprocity.