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rs1047840

From SNPedia

Orientationplus
Stabilizedplus
Make rs1047840(A;A)
Make rs1047840(A;G)
Make rs1047840(G;G)
ReferenceGRCh38 38.1/141
Chromosome1
Position241878999
GeneEXO1
is asnp
is mentioned by
dbSNPrs1047840
ebirs1047840
HLIrs1047840
Exacrs1047840
Varsomers1047840
Maprs1047840
PheGenIrs1047840
hapmaprs1047840
1000 genomesrs1047840
hgdprs1047840
ensemblrs1047840
gopubmedrs1047840
geneviewrs1047840
scholarrs1047840
googlers1047840
pharmgkbrs1047840
gwascentralrs1047840
openSNPrs1047840
23andMers1047840
23andMe allrs1047840
SNP Nexus

SNPshotrs1047840
SNPdbers1047840
MSV3drs1047840
GWAS Ctlgrs1047840
GMAF0.3609
Max Magnitude
? (A;A) (A;G) (G;G) 28
rs1047840, also known as K589E, is a SNP in the EXO1 gene.

A study of 1,272 breast cancer Taiwanese patients concluded that the rs1047840(A) allele conferred a significantly (p=0.000025) increased risk of breast cancer.[PMID 19846925]


[PMID 19515603] Interaction of Exo1 genotypes and smoking habit in oral cancer in Taiwan


[PMID 20337148] Single-nucleotide polymorphism of the Exo1 gene: association with gastric cancer susceptibility and interaction with smoking in Taiwan


[PMID 22146767] A Single Nucleotide Polymorphism in EXO1 Gene is Associated With Cervical Cancer Susceptibility in Chinese Patients


[PMID 22573488] EGFR exon 19 in-frame deletion and polymorphisms of DNA repair genes in never-smoking female lung adenocarcinoma patients


[PMID 18079015] Potentially functional polymorphisms of EXO1 and risk of lung cancer in a Chinese population: A case-control analysis.


[PMID 18191955OA-icon.png] Correlating observed odds ratios from lung cancer case-control studies to SNP functional scores predicted by bioinformatic tools.


[PMID 18559551] Pathway analysis of single-nucleotide polymorphisms potentially associated with glioblastoma multiforme susceptibility using random forests.


[PMID 19331228] Lung cancer susceptibility and genetic polymorphisms of Exo1 gene in Taiwan.


GET Evidence
EXO1-E589K
aa_change Glu589Lys
aa_change_short E589K
impact not reviewed
qualified_impact Insufficiently evaluated not reviewed
overall_frequency 0.409184
summary