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rs10490923

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(G;G) 0 common in complete genomics
Make rs10490923(A;A)
Make rs10490923(A;G)
ReferenceGRCh38 38.1/142
Chromosome10
Position122454735
GeneARMS2
is asnp
is mentioned by
dbSNPrs10490923
ebirs10490923
HLIrs10490923
Exacrs10490923
Varsomers10490923
Maprs10490923
PheGenIrs10490923
hapmaprs10490923
1000 genomesrs10490923
hgdprs10490923
ensemblrs10490923
gopubmedrs10490923
geneviewrs10490923
scholarrs10490923
googlers10490923
pharmgkbrs10490923
gwascentralrs10490923
openSNPrs10490923
23andMers10490923
23andMe allrs10490923
SNP Nexus

SNPshotrs10490923
SNPdbers10490923
MSV3drs10490923
GWAS Ctlgrs10490923
GMAF0.07254
Max Magnitude0
? (A;A) (A;G) (G;G) 28

[PMID 19268887] ARMS2 (LOC387715) Variants in Japanese Patients with Exudative Age-related Macular Degeneration and Polypoidal Choroidal Vasculopathy.


[PMID 19933179OA-icon.png] Inverse association of female hormone replacement therapy and oral contraceptive use with age-related macular degeneration and interactions with ARMS2 polymorphisms


[PMID 16080115OA-icon.png] Susceptibility genes for age-related maculopathy on chromosome 10q26.


[PMID 16642439OA-icon.png] Cigarette smoking strongly modifies the association of LOC387715 and age-related macular degeneration.


[PMID 17325155OA-icon.png] The LOC387715 polymorphism and age-related macular degeneration: replication in three case-control samples.


[PMID 18162041OA-icon.png] Neovascular age-related macular degeneration risk based on CFH, LOC387715/HTRA1, and smoking.


[PMID 18688167] Polymorphisms in the LOC387715/ARMS2 putative gene and the risk for Alzheimer's disease.


[PMID 19259132OA-icon.png] Multilocus analysis of age-related macular degeneration.


GET Evidence
ARMS2-R3H
aa_change Arg3His
aa_change_short R3H
impact not reviewed
qualified_impact Insufficiently evaluated not reviewed
overall_frequency 0.0963633
summary



[PMID 23534868] CFH (rs1410996), HTRA1 (rs112000638) and ARMS2 (rs10490923) Gene Polymorphisms are Associated with AMD Risk in Spanish Patients