rs1050501

plus

Geno	Mag	Summary
(T;T)	0	common in complete genomics

Make rs1050501(C;C)

Make rs1050501(C;T)

Reference

GRCh38 38.1/141

Chromosome

1

Position

161674008

Gene

FCGR2B

is a	snp
is	mentioned by
dbSNP	rs1050501
dbSNP (classic)	rs1050501
ClinGen	rs1050501
ebi	rs1050501
HLI	rs1050501
Exac	rs1050501
Gnomad	rs1050501
Varsome	rs1050501
LitVar	rs1050501
Map	rs1050501
PheGenI	rs1050501
Biobank	rs1050501
1000 genomes	rs1050501
hgdp	rs1050501
ensembl	rs1050501
geneview	rs1050501
scholar	rs1050501
google	rs1050501
pharmgkb	rs1050501
gwascentral	rs1050501
openSNP	rs1050501
23andMe	rs1050501
SNPshot	rs1050501
SNPdbe	rs1050501
MSV3d	rs1050501
GWAS Ctlg	rs1050501

GMAF

0.1869

Max Magnitude

0

[PMID 19640933] FCGR2B gene polymorphism rather than FCGR2A, FCGR3A and FCGR3B is associated with anti-GBM disease in Chinese

OMIM	604590
Desc
Variant	0002
Related	also

[PMID 22416796] The FCGR2B rs10917661 polymorphism may confer susceptibility to ankylosing spondylitis in Han Chinese: a case-control study

ClinVar
Risk	rs1050501(C;C)
Alt	rs1050501(C;C)
Reference	Rs1050501(T;T)
Significance	Other
Disease	Systemic lupus erythematosus Malaria
Variation	info
Gene	FCGR2B
CLNDBN	Systemic lupus erythematosus, susceptibility to Malaria, resistance to
Reversed	0
HGVS	NC_000001.10:g.161643798T>C
CLNSRC	OMIM Allelic Variant UniProtKB (protein)
CLNACC	RCV000005800.2, RCV000005801.2,

[PMID 16531013] Association of Fcgamma receptor IIB gene polymorphism with genetic susceptibility to systemic lupus erythematosus in Chinese populations--a family-based association study.

[PMID 18625651] Genetic susceptibility and haplotype analysis between Fcgamma receptor IIB and IIIA gene with systemic lupus erythematosus in Chinese population.

[PMID 19421223 ] Fcgamma receptors: structure, function and role as genetic risk factors in SLE.

[PMID 20508037 ] Copy number, linkage disequilibrium and disease association in the FCGR locus.

[PMID 24586589 ] Functional fcgamma receptor polymorphisms are associated with human allergy [PMID 22922574] Fcgamma receptor polymorphisms do not predict response to intravenous immunoglobulin in myasthenia gravis.