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rs1051730(C;C)

From SNPedia

Smokes normal (lower) number of cigarettes if a smoker.
Is agenotype
ofrs1051730
GeneCHRNA3
Chromosome15
Position78,601,997
mentionedby
Magnitude2
ReputeGood
Geno Mag Summary
(C;C) 2 Smokes normal (lower) number of cigarettes if a smoker.
(C;T) 2 1.3x increased risk of lung cancer
(T;T) 2.5 1.8x increased risk of lung cancer; reduced response to alcohol, therefore possibly increased risk of alcohol abuse

Less nicotine dependence. Also smokes each cigarette less deeply. Therefore there is a reduced risk of lung cancer and a reduced (0.8x) risk of Peripheral Artery Disease. This doesn't affect whether people start smoking though.