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rs1059702

From SNPedia

Orientationminus
Stabilizedminus
Make rs1059702(C;C)
Make rs1059702(C;T)
Make rs1059702(T;T)
ReferenceGRCh38 38.1/141
ChromosomeX
Position154018741
GeneIRAK1
is asnp
is mentioned by
dbSNPrs1059702
ebirs1059702
HLIrs1059702
Exacrs1059702
Varsomers1059702
Maprs1059702
PheGenIrs1059702
hapmaprs1059702
1000 genomesrs1059702
hgdprs1059702
ensemblrs1059702
gopubmedrs1059702
geneviewrs1059702
scholarrs1059702
googlers1059702
pharmgkbrs1059702
gwascentralrs1059702
openSNPrs1059702
23andMers1059702
23andMe allrs1059702
SNP Nexus

SNPshotrs1059702
SNPdbers1059702
MSV3drs1059702
GWAS Ctlgrs1059702
GMAF0.3222
Max Magnitude
? (C;C) (C;T) (T;T) 28

[PMID 21933552] Functional polymorphism in exon 5 and variant haplotype of the interleukin-1 receptor-associated kinase 1 gene are associated with susceptibility to and severity of sepsis in the Chinese population


[PMID 17382928OA-icon.png] The association between innate immunity gene (IRAK1) and C-reactive protein in the Diabetes Heart Study.


[PMID 19505919OA-icon.png] Toll-like receptor signaling pathway variants and prostate cancer mortality.


[PMID 21898345] Evidence of the contribution of the X chromosome to systemic sclerosis susceptibility: association with the functional IRAK1 196Phe/532Ser haplotype.


GET Evidence
IRAK1-F196S
aa_change Phe196Ser
aa_change_short F196S
impact not reviewed
qualified_impact Insufficiently evaluated not reviewed
overall_frequency 0.896359
summary



[PMID 23233309] An activity-enhancing variant of IRAK1 and an MECP2-IRAK1 haplotype associating with increased susceptibility to rheumatoid arthritis


[PMID 23444193OA-icon.png] New insight on the Xq28 association with systemic sclerosis


[PMID 22904263OA-icon.png] Fine mapping of Xq28: both MECP2 and IRAK1 contribute to risk for systemic lupus erythematosus in multiple ancestral groups.


[PMID 23435933] Association of interleukin-1 receptor-associated kinase (IRAK1) gene polymorphisms (rs3027898, rs1059702) with systemic lupus erythematosus in a Chinese Han population.


[PMID 24709033] Analysis of two autoimmunity genes, IRAK1 and MECP2, in giant cell arteritis