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rs1064039(A;A)

From SNPedia

Higher risk for age-related macular degeneration; slightly higher Alzheimers risk in Caucasians but not Asians
Is agenotype
ofrs1064039
GeneCST3
Chromosome20
Position23,637,790
mentionedby
Magnitude2
ReputeBad
Geno Mag Summary
(A;A) 2 Higher risk for age-related macular degeneration; slightly higher Alzheimers risk in Caucasians but not Asians
(A;G) 1.2 slightly higher risk for Alzheimers in Caucasians but not Asians
(G;G) 0 common in clinvar

Higher risk (2 or 3 fold, perhaps) for age-related macular degeneration has been reported based on a relatively small study of German patients.

In Caucasians but not Asians, a meta-analysis concluded that the (A) allele was associated with about a 1.5x higher risk for Alzheimers in both dominant and recessive models.