| Higher risk for age-related macular degeneration; slightly higher Alzheimers risk in Caucasians but not Asians |
| Geno
|
Mag
|
Summary
|
| (A;A)
|
2
|
Higher risk for age-related macular degeneration; slightly higher Alzheimers risk in Caucasians but not Asians
|
| (A;G)
|
1.2
|
slightly higher risk for Alzheimers in Caucasians but not Asians
|
| (G;G)
|
0
|
common in clinvar
|
Higher risk (2 or 3 fold, perhaps) for age-related macular degeneration has been reported based on a relatively small study of German patients.
In Caucasians but not Asians, a meta-analysis concluded that the (A) allele was associated with about a 1.5x higher risk for Alzheimers in both dominant and recessive models.
