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rs107251

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 0 common in complete genomics
Make rs107251(C;T)
Make rs107251(T;T)
ReferenceGRCh38 38.1/141
Chromosome19
Position4176088
GeneSIRT6
is asnp
is mentioned by
dbSNPrs107251
ebirs107251
HLIrs107251
Exacrs107251
Varsomers107251
Maprs107251
PheGenIrs107251
hapmaprs107251
1000 genomesrs107251
hgdprs107251
ensemblrs107251
gopubmedrs107251
geneviewrs107251
scholarrs107251
googlers107251
pharmgkbrs107251
gwascentralrs107251
openSNPrs107251
23andMers107251
23andMe allrs107251
SNP Nexus

SNPshotrs107251
SNPdbers107251
MSV3drs107251
GWAS Ctlgrs107251
GMAF0.1786
Max Magnitude0
? (C;C) (C;T) (T;T) 28

One study found that individuals with either the CC or CT genotype at rs107251 within SIRT6 displayed >5-year mean survival advantages compared to the TT genotype (5.5 and 5.9 years, respectively; q-value  = 0.012). [PMID 25541994OA-icon.png]


[PMID 22087257OA-icon.png] Association of the Sirtuin and Mitochondrial Uncoupling Protein Genes with Carotid Plaque


[PMID 25541994OA-icon.png] SIRT6 Minor Allele Genotype Is Associated with >5-Year Decrease in Lifespan in an Aged Cohort.