|(A;A)||2||influences working memory|
|(A;C)||1.3x increased risk for alcoholism|
[PMID 19796663] Influence of DRD2 and ANKK1 genotypes on apomorphine-induced growth hormone (GH) response in alcohol-dependent patients
[PMID 19940176] Functional Variation of the Dopamine D2 Receptor Gene Is Associated with Emotional Control as well as Brain Activity and Connectivity during Emotion Processing in Humans
[PMID 19512960] Genetic diagnostics of functional variants of the human dopamine D2 receptor gene
[PMID 20179754] Genetically Determined Measures of Striatal D2 Signaling Predict Prefrontal Activity during Working Memory Performance
[PMID 19393722] Genetic contributions to avoidance-based decisions: striatal D2 polymorphisms
[PMID 21087673] D2 receptor genotype and striatal dopamine signaling predict motor cortical activity and behavior in humans
[PMID 21150907] Intronic polymorphisms affecting alternative splicing of human dopamine D2 receptor are associated with cocaine abuse.
[PMID 22569179] Rs1076560, a functional variant of the dopamine D2 receptor gene, confers risk of schizophrenia in Han Chinese
[PMID 22745721] Cannabis-Dependence Risk Relates to Synergism between Neuroticism and Proenkephalin SNPs Associated with Amygdala Gene Expression: Case-Control Study
[PMID 18077373] Polymorphisms in human dopamine D2 receptor gene affect gene expression, splicing, and neuronal activity during working memory.
[PMID 19321766] Dopamine DRD2 polymorphism alters reversal learning and associated neural activity.
[PMID 20146828] Dopamine D2 receptor polymorphisms and susceptibility to alcohol dependence in Indian males: a preliminary study.
[PMID 20617039] Alcoholism and alternative splicing of candidate genes.
[PMID 21187413] DRD2/AKT1 interaction on D2 c-AMP independent signaling, attentional processing, and response to olanzapine treatment in schizophrenia.
[PMID 21645585] Resting posterior minus frontal EEG slow oscillations is associated with extraversion and DRD2 genotype.
|qualified_impact||Insufficiently evaluated pharmacogenetic|
[PMID 24322206] Contrasting changes in DRD1 and DRD2 splice variant expression in schizophrenia and affective disorders, and associations with SNPs in postmortem brain
[PMID 24359476] The Dopamine Receptor D2 (DRD2) SNP rs1076560 is Associated with Opioid Addiction
[PMID 24424781] DRD2 genotype predicts prefrontal activity during working memory after stimulation of D2 receptors with bromocriptine
[PMID 21976709] DRD2 genotype-based variation of default mode network activity and of its relationship with striatal DAT binding.