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rs10801935

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) normal
(A;C) normal
(C;C) 1.6 0.3x decreased risk of breast cancer
ReferenceGRCh38 38.1/141
Chromosome1
Position117179265
GeneVTCN1
is asnp
is mentioned by
dbSNPrs10801935
ebirs10801935
HLIrs10801935
Exacrs10801935
Varsomers10801935
Maprs10801935
PheGenIrs10801935
hapmaprs10801935
1000 genomesrs10801935
hgdprs10801935
ensemblrs10801935
gopubmedrs10801935
geneviewrs10801935
scholarrs10801935
googlers10801935
pharmgkbrs10801935
gwascentralrs10801935
openSNPrs10801935
23andMers10801935
23andMe allrs10801935
SNP Nexus

SNPshotrs10801935
SNPdbers10801935
MSV3drs10801935
GWAS Ctlgrs10801935
GMAF0.3838
Max Magnitude1.6
? (A;A) (A;C) (C;C) 28
rs10801935 is a SNP in the V-set domain containing T cell activation inhibitor 1 VTCN1 gene, which is also known as B7-H4.

A study of 500 Chinese Han women with breast cancer (and an equal number of matched controls) concluded that the rs10801935(C;C) genotype showed a significantly decreased risk of breast cancer (odds ratio 0.328, CI: 0.145-0.739).[PMID 19903360OA-icon.png]


[PMID 24125968] An investigation of the effects of FGFR2 and B7-H4 polymorphisms in breast cancer