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rs10830962

From SNPedia

Orientationplus
Stabilizedplus
Make rs10830962(C;C)
Make rs10830962(C;G)
Make rs10830962(G;G)
ReferenceGRCh38 38.1/141
Chromosome11
Position92965261
is asnp
is mentioned by
dbSNPrs10830962
ebirs10830962
HLIrs10830962
Exacrs10830962
Varsomers10830962
Maprs10830962
PheGenIrs10830962
hapmaprs10830962
1000 genomesrs10830962
hgdprs10830962
ensemblrs10830962
gopubmedrs10830962
geneviewrs10830962
scholarrs10830962
googlers10830962
pharmgkbrs10830962
gwascentralrs10830962
openSNPrs10830962
23andMers10830962
23andMe allrs10830962
SNP Nexus

SNPshotrs10830962
SNPdbers10830962
MSV3drs10830962
GWAS Ctlgrs10830962
GMAF0.4917
Max Magnitude
? (C;C) (C;G) (G;G) 28
[PMID 19088850OA-icon.png] rs10830962, rs4753426, and rs10830963 were significantly associated with higher fasting plasma glucose concentrations and reduced OGTT- and IVGTT-induced insulin release. rs3781638 displayed significant association with lower fasting plasma glucose levels and increased OGTT-induced insulin release


[PMID 22233651OA-icon.png] A Genome-Wide Association Study of Gestational Diabetes Mellitus in Korean Women

GWAS snp
PMID [PMID 21909109]
Trait
Title Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.
Risk Allele C
P-val 1E-16
Odds Ratio 0.0445 [0.034-0.055] mg/dL increase
GWAS snp
PMID [PMID 22399527OA-icon.png]
Trait
Title Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits.
Risk Allele G
P-val 5E-16
Odds Ratio 0.1200 None


[PMID 19184136OA-icon.png] Examination of association of genes in the serotonin system to autism.


[PMID 20959387] Association of rs10830963 and rs10830962 SNPs in the melatonin receptor (MTNR1B) gene among Han Chinese women with polycystic ovary syndrome.

GWAS snp
PMID [PMID 23575436]
Trait Glycemic traits
Title New susceptibility loci in MYL2, C12orf51 and OAS1 associated with 1-h plasma glucose as predisposing risk factors for type 2 diabetes in the Korean population.
Risk Allele C
P-val 5E-13
Odds Ratio .04 [0.029-0.053] mmol-1 increase


[PMID 24157813] Association between Genetic Variations in MTNR1A and MTNR1B Genes and Gestational Diabetes Mellitus in Han Chinese Women


[PMID 23611530] Genetics of melatonin receptor type 2 is associated with left ventricular function in hypertensive patients treated according to guidelines.