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rs10896449

From SNPedia

Orientationplus
Stabilizedplus
Make rs10896449(A;A)
Make rs10896449(A;G)
Make rs10896449(G;G)
ReferenceGRCh38 38.1/141
Chromosome11
Position69227200
is asnp
is mentioned by
dbSNPrs10896449
ebirs10896449
HLIrs10896449
Exacrs10896449
Varsomers10896449
Maprs10896449
PheGenIrs10896449
hapmaprs10896449
1000 genomesrs10896449
hgdprs10896449
ensemblrs10896449
gopubmedrs10896449
geneviewrs10896449
scholarrs10896449
googlers10896449
pharmgkbrs10896449
gwascentralrs10896449
openSNPrs10896449
23andMers10896449
23andMe allrs10896449
SNP Nexus

SNPshotrs10896449
SNPdbers10896449
MSV3drs10896449
GWAS Ctlgrs10896449
GMAF0.4063
Max Magnitude
? (A;A) (A;G) (G;G) 28
nature identifies rs10486567 rs10993994 rs10896449 in prostate cancer
Neighborrs7931342
Distance170
GWAS
SNP rs10896449
PubMedID [PMID 18264096]
Condition Prostate cancer (aggressive)
Gene Intergenic
Risk Allele G
pValue 2.00E-009
OR 1.1
95% CI 0.98-1.23


[PMID 19505914OA-icon.png] Two independent prostate cancer risk-associated Loci at 11q13

OMIM611958
DescPROSTATE CANCER, HEREDITARY, 14; HPC14
Variant
Relatedalso

[PMID 19902474] Replication of prostate cancer risk loci on 8q24, 11q13, 17q12, 19q33, and Xp11 in African Americans



[PMID 21531787OA-icon.png] Fine mapping of a region of chromosome 11q13 reveals multiple independent loci associated with risk of prostate cancer


[PMID 22459122OA-icon.png] Interactions Between Genome-wide Significant Genetic Variants and Circulating Concentrations of Insulin-like Growth Factor 1, Sex Hormones, and Binding Proteins in Relation to Prostate Cancer Risk in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium


[PMID 18708398OA-icon.png] Multiple novel prostate cancer predisposition loci confirmed by an international study: the PRACTICAL Consortium.


[PMID 18794092OA-icon.png] Association of prostate cancer risk variants with clinicopathologic characteristics of the disease.


[PMID 19366831OA-icon.png] Analysis of recently identified prostate cancer susceptibility loci in a population-based study: associations with family history and clinical features.


[PMID 19434657OA-icon.png] Individual and cumulative effect of prostate cancer risk-associated variants on clinicopathologic variables in 5,895 prostate cancer patients.


[PMID 19549807OA-icon.png] Prostate cancer risk associated loci in African Americans.


[PMID 19567509OA-icon.png] Genetic variants and prostate cancer risk: candidate replication and exploration of viral restriction genes.


[PMID 20039378OA-icon.png] Estimation of genotype relative risks from pedigree data by retrospective likelihoods.


[PMID 20569440OA-icon.png] Alterations in LMTK2, MSMB and HNF1B gene expression are associated with the development of prostate cancer.


[PMID 20690139] Meta-analysis of genome-wide and replication association studies on prostate cancer.


[PMID 21390317OA-icon.png] Characterizing associations and SNP-environment interactions for GWAS-identified prostate cancer risk markers--results from BPC3.


[PMID 21520160] Prostate cancer risk variants are not associated with disease progression.


[PMID 22468268OA-icon.png] Comprehensive resequence analysis of a 123-kb region of chromosome 11q13 associated with prostate cancer.


GET Evidence
rs10896449
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.444444
summary



[PMID 23405784] [Susceptibility to prostate cancer in Han Chinese: single nucleotide polymorphism analysis of 1 667 cases]


[PMID 23573233OA-icon.png] Characterization of SNPs Associated with Prostate Cancer in Men of Ashkenazic Descent from the Set of GWAS Identified SNPs: Impact of Cancer Family History and Cumulative SNP Risk Prediction