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rs10913469

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(T;T) 0 common in complete genomics
Make rs10913469(C;C)
Make rs10913469(C;T)
ReferenceGRCh38 38.1/141
Chromosome1
Position177944384
GeneSEC16B
is asnp
is mentioned by
dbSNPrs10913469
ebirs10913469
HLIrs10913469
Exacrs10913469
Varsomers10913469
Maprs10913469
PheGenIrs10913469
hapmaprs10913469
1000 genomesrs10913469
hgdprs10913469
ensemblrs10913469
gopubmedrs10913469
geneviewrs10913469
scholarrs10913469
googlers10913469
pharmgkbrs10913469
gwascentralrs10913469
openSNPrs10913469
23andMers10913469
23andMe allrs10913469
SNP Nexus

SNPshotrs10913469
SNPdbers10913469
MSV3drs10913469
GWAS Ctlgrs10913469
GMAF0.2346
Max Magnitude0
? (C;C) (C;T) (T;T) 28
GWAS snp
PMID [PMID 19079260]
Trait Body mass index
Title Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity
Risk Allele C
P-val 6E-8
Odds Ratio 3.36 [2.14-4.58] % SD


[PMID 19851340] Association between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population



[PMID 20061430] Obesity Susceptibility Genetic Variants Identified from Recent Genome-Wide Association Studies: Implications in a Chinese Population



[PMID 21796141] Computed tomography analysis of the association between the SH2B1 rs7498665 single-nucleotide polymorphism and visceral fat area


[PMID 21912638OA-icon.png] Studies of metabolic phenotypic correlates of 15 obesity associated gene variants

[PMID 19478790OA-icon.png] The role of obesity-associated loci identified in genome-wide association studies in the determination of pediatric BMI.

[PMID 19553259OA-icon.png] Common body mass index-associated variants confer risk of extreme obesity.

[PMID 20127379OA-icon.png] From monogenic to polygenic obesity: recent advances.

[PMID 20712903OA-icon.png] Obesity and diabetes genes are associated with being born small for gestational age: results from the Auckland Birthweight Collaborative study.

[PMID 20824172OA-icon.png] Physical activity attenuates the genetic predisposition to obesity in 20,000 men and women from EPIC-Norfolk prospective population study.


GET Evidence
rs10913469
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.1875
summary



[PMID 23424664OA-icon.png] Study of 11 BMI-associated loci identified in GWAS for associations with central obesity in the Chinese children


[PMID 23935507OA-icon.png] Gene × physical activity interactions in obesity: combined analysis of 111,421 individuals of European ancestry


[PMID 24269186] An obesity genetic risk score is associated with metabolic syndrome in Chinese children


[PMID 23408508OA-icon.png] Obesity-susceptibility loci and the tails of the pediatric BMI distribution


[PMID 23121087] Sex-dependent associations of genetic variants identified by GWAS with indices of adiposity and obesity risk in a Chinese children population.


[PMID 25492288] [Impact of obesity-related gene polymorphism on risk of obesity and metabolic disorder in childhood]