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rs10936599

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 2 longer telomeres, longer life?
(T;T) 2 shorter telomeres, shorter life?
Make rs10936599(C;T)
ReferenceGRCh38 38.1/141
Chromosome3
Position169774313
GeneMYNN
is asnp
is mentioned by
dbSNPrs10936599
ebirs10936599
HLIrs10936599
Exacrs10936599
Varsomers10936599
Maprs10936599
PheGenIrs10936599
hapmaprs10936599
1000 genomesrs10936599
hgdprs10936599
ensemblrs10936599
gopubmedrs10936599
geneviewrs10936599
scholarrs10936599
googlers10936599
pharmgkbrs10936599
gwascentralrs10936599
openSNPrs10936599
23andMers10936599
23andMe allrs10936599
SNP Nexus

SNPshotrs10936599
SNPdbers10936599
MSV3drs10936599
GWAS Ctlgrs10936599
GMAF0.3035
Max Magnitude2
? (C;C) (C;T) (T;T) 28
GWAS snp
PMID [PMID 20190752OA-icon.png]
Trait Celiac disease
Title Multiple common variants for celiac disease influencing immune gene expression
Risk Allele A
P-val 5E-7
Odds Ratio 1.12 [1.07-1.16]
GWAS snp
PMID [PMID 20972440]
Trait
Title Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33
Risk Allele C
P-val 3E-8
Odds Ratio 1.0400 [1.04-1.10]


[PMID 21708826OA-icon.png] TERC polymorphisms are associated both with susceptibility to colorectal cancer and with longer telomeres

GWAS snp
PMID [PMID 21833088OA-icon.png]
Trait
Title Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.
Risk Allele G
P-val 7E-7
Odds Ratio 1.1000 [1.08-1.11]


[PMID 22045029] Relationship between 16 susceptibility loci and colorectal cancer phenotype in 3146 patients.

GWAS snp
PMID [PMID 23535734OA-icon.png]
Trait Telomere length
Title Identification of seven loci affecting mean telomere length and their association with disease.
Risk Allele T
P-val 3E-31
Odds Ratio .10 [0.081-0.113] unit decrease


[PMID 24449210] Inherited genetic susceptibility to monoclonal gammopathy of unknown significance


[PMID 24292274] A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia


[PMID 22999960OA-icon.png] Much of the genetic risk of colorectal cancer is likely to be mediated through susceptibility to adenomas.

GWAS snp
PMID [PMID 24163127OA-icon.png]
Trait Bladder cancer
Title Genome-wide association study identifies multiple loci associated with bladder cancer risk.
Risk Allele C
P-val 5E-9
Odds Ratio 1.18 [1.11-1.23]


[PMID 24875374OA-icon.png] Variation in the Association Between Colorectal Cancer Susceptibility Loci and Colorectal Polyps by Polyp Type


[PMID 24904205OA-icon.png] Association between previously identified loci affecting telomere length and coronary heart disease (CHD) in Han Chinese population


[PMID 24978480OA-icon.png] A Colorectal Cancer Susceptibility New Variant at 4q26 in the Spanish Population Identified by Genome-Wide Association Analysis

GWAS snp
PMID [PMID 23955597]
Trait Multiple myeloma
Title Common variation at 3q26.2, 6p21.33, 17p11.2 and 22q13.1 influences multiple myeloma risk.
Risk Allele G
P-val 9E-14
Odds Ratio 1.26 [1.18-1.33]