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rs10937275

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(G;G) 0
Make rs10937275(A;A)
Make rs10937275(A;G)
ReferenceGRCh38 38.1/141
Chromosome3
Position186933001
GeneLDLRAD2, ST6GAL1
is asnp
is mentioned by
dbSNPrs10937275
ebirs10937275
HLIrs10937275
Exacrs10937275
Varsomers10937275
Maprs10937275
PheGenIrs10937275
hapmaprs10937275
1000 genomesrs10937275
hgdprs10937275
ensemblrs10937275
gopubmedrs10937275
geneviewrs10937275
scholarrs10937275
googlers10937275
pharmgkbrs10937275
gwascentralrs10937275
openSNPrs10937275
23andMers10937275
23andMe allrs10937275
SNP Nexus

SNPshotrs10937275
SNPdbers10937275
MSV3drs10937275
GWAS Ctlgrs10937275
GMAF0.08356
Max Magnitude0
? (A;A) (A;G) (G;G) 28
In HLA-B*5701 carrier cases, i.e. rs2395029(G) carriers, rs10937275 showed an increased in risk for drug-induced liver injury for patients taking flucloxacillin. The odds ratio was 4.1 (p = 1.4 x 10(-8)).[PMID 19483685]
OMIM142830
DescMAJOR HISTOCOMPATIBILITY COMPLEX, CLASS I, B; HLA-B
Variant
Relatedalso


OMIM604676
DescHLA COMPLEX P5 GENE; HCP5
Variant
Relatedalso


GET Evidence
rs10937275
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.90625
summary